Emerging Graphitic Carbon Nitride-based Nanobiomaterials for Biological Applications

Abstract

Graphitic carbon nitride (g-CN) based nanostructures are distinctive materials with unique compositional, structural, optical, and electronic properties with exceptional band structure, moderate surface area, and exceptional thermal and chemical stability. Because of these properties, g-CN based nanomaterials have shown promising applications and higher performance in the biological avenue. This review covers the state-of-the-art synthetic strategies used for the preparation of the materials, the basic structure, and a panorama of different optimization strategies leading to improved physicochemical properties responsible for the biological application. The following sections include the recent progress in the use of g-CN based nanobiomaterials for biosensors, bioimaging, photodynamic therapy, drug delivery, chemotherapy, and the antimicrobial segment. Furthermore, we have summarized the role and evaluation of biosafety and biocompatibility of the material. Finally, the unresolved issues, plausible challenges, current status, and future perspectives for the development and design of g-CN have been summarized and are expected to promote a clinical path for the medical sector and human well-being.

Keywords: and antimicrobial; bioimaging; biological avenue; biosafety and biocompatibility; biosensors; graphitic carbon nitride; nanobiomaterials; photodynamic therapy.