Metabolism of 5-ASA by the gut microbiome

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Comment

Jordan Hindson. Nat Rev Gastroenterol Hepatol. 2023 May.

. 2023 May;20(5):269.

doi: 10.1038/s41575-023-00777-0.

No abstract available

Comment on

Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.
Mehta RS, Mayers JR, Zhang Y, Bhosle A, Glasser NR, Nguyen LH, Ma W, Bae S, Branck T, Song K, Sebastian L, Pacheco JA, Seo HS, Clish C, Dhe-Paganon S, Ananthakrishnan AN, Franzosa EA, Balskus EP, Chan AT, Huttenhower C. Mehta RS, et al. Nat Med. 2023 Mar;29(3):700-709. doi: 10.1038/s41591-023-02217-7. Epub 2023 Feb 23. Nat Med. 2023. PMID: 36823301 Free PMC article.

1. Mehta, R. S. et al. Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nat. Med. 29, 700–709 (2023) - DOI - PubMed