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Observational Study
. 2023 Apr 5;23(1):215.
doi: 10.1186/s12877-023-03942-x.

Assessment of drug-related problems at the emergency department in older patients living with frailty: pharmacist-led medication reviews within a geriatric care team

Merel van Nuland  1 , Madelon Butterhoff  2 , Karin Verwijmeren  2 , Florine Berger  2 , Vera M Hogervorst  3 , Annemarieke de Jonghe  3 , Paul D van der Linden  2
Affiliations
Observational Study

Assessment of drug-related problems at the emergency department in older patients living with frailty: pharmacist-led medication reviews within a geriatric care team

Merel van Nuland et al. BMC Geriatr. .

Abstract

Background: Older patients are vulnerable to experiencing drug related problems (DRPs), which may result in emergency department (ED) visits. However, it is not standard practice to conduct medications reviews during ED visit. The aim of this study was to assess the number of DRPs in older patients living with frailty at the ED, identified through pharmacist-led medication reviews within a geriatric care team, and to determine the acceptance rate of pharmacists' recommendations among hospital physicians and general practitioners or elderly care specialists.

Methods: A retrospective observational study was performed in patients ≥ 70 years living with frailty at the ED at Tergooi Medical Center. Pharmacist-led medication reviews were conducted to identify and classify DRPs as part of a larger geriatric assessment. The acceptance rate of given recommendations was determined during follow-up.

Results: A total of 356 ED visits were included. The mean (standard deviation, SD) age of patients was 83 (6.8) years. About 76% of patients had at least one DRP. In total, 548 DRPs were identified with a mean of 1.5 DRP (SD 1.3) per patient. The acceptance rate of medication recommendations in admitted patients was 55%, and 32% among general practitioners/elderly care specialists in discharged patients.

Conclusions: Pharmacist-led medication reviews as part of a geriatric care team identified DRPs in 76% of older patients living with frailty at the ED. The acceptance rate was substantially higher in admitted patients compared to discharged patients.

Keywords: Drug-related problem (DRP); Elderly; Emergency department; Frailty; Medication review.

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Conflict of interest statement

The authors have no relevant financial or non-financial interests to disclose.

References

    1. Hohl CM, Woo SA, Cragg A, Wickham ME, Ackerley C, Scheuermeyer F, et al. Repeat adverse drug events associated with outpatient medications: a descriptive analysis of 3 observational studies in British Columbia, Canada. CMAJ Open. 2019;7:E446–53. doi: 10.9778/cmajo.20180190. - DOI - PMC - PubMed
    1. Dormann H, Sonst A, Müller F, Vogler R, Patapovas A, Pfistermeister B, et al. Adverse drug events in older patients admitted as an emergency: the role of potentially inappropriate medication in elderly people (PRISCUS) Dtsch Arztebl Int. 2013;110:213–219. - PMC - PubMed
    1. Reichardt LA, Aarden JJ, van Seben R, van der Schaaf M, Engelbert RHH, Bosch JA, et al. Unravelling the potential mechanisms behind hospitalization-associated disability in older patients; the Hospital-Associated Disability and impact on daily Life (Hospital-ADL) cohort study protocol. BMC Geriatr. 2016;16:59. doi: 10.1186/s12877-016-0232-3. - DOI - PMC - PubMed
    1. Leendertse AJ, Egberts ACG, Stoker LJ, van den Bemt PMLA, HARM Study Group Frequency of and risk factors for preventable medication-related hospital admissions in the Netherlands. Arch Intern Med. 2008;168:1890–6. - PubMed
    1. Conroy T, Heuzenroeder L, Feo R. In-hospital interventions for reducing readmissions to acute care for adults aged 65 and over: An umbrella review. Int J Qual Health Care. 2020;32:414–430. doi: 10.1093/intqhc/mzaa064. - DOI - PubMed

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