Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Mar 3;15(3):e35730.
doi: 10.7759/cureus.35730. eCollection 2023 Mar.

Peritoneal Carcinomatosis From Malignant Melanoma After Wide Local Excision of a T1a Lesion: A Case Report

Matthew Hager  1 , John Miller  1 , Adam Wegener  1 , James Yon  1
Affiliations
Case Reports

Peritoneal Carcinomatosis From Malignant Melanoma After Wide Local Excision of a T1a Lesion: A Case Report

Matthew Hager et al. Cureus. .

Abstract

Cutaneous melanoma is an aggressive skin cancer with a high propensity for distant metastasis. Peritoneal metastasis from cutaneous malignant melanoma is extremely rare and associated with a low five-year overall survival rate. This report reviews a case of a 78-year-old man with peritoneal carcinomatosis after a wide local excision of a T1a invasive malignant melanoma of the scalp 10 months prior. Although rare, patients with a recent history of melanoma who present with obscure or odd symptoms should be worked up for metastatic disease by their surgeon or medical oncologist. Carcinomatosis can develop, and early treatment with immunotherapy has been shown to improve five-year overall survival and progression-free survival in patients with advanced melanoma.

Keywords: cutaneous malignant melanoma; lactate dehydrogenase; melanoma; metastatic melanoma; peritoneal carcinomatosis; peritoneal metastasis; skin cancer.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. CT abdomen and pelvis with omental caking on December 22, 2020
Figure 2
Figure 2. Abdominal ascites and nodularity of the omentum suggestive of peritoneal carcinomatosis seen on chest CT on December 28, 2020
Figure 3
Figure 3. H&E stain of peritoneal biopsy
Figure 4
Figure 4. SOX-10 stain of peritoneal biopsy
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. The American Society of Clinical Oncology. Cancer.Net; [ Mar; 2022 ]. 2022. The American Society of Clinical Oncology. Melanoma: statistics.
    1. Increased risk of second primary cancers after a diagnosis of melanoma. Bradford PT, Freedman DM, Goldstein AM, Tucker MA. Arch Dermatol. 2010;146:265–272. - PMC - PubMed
    1. Peritoneal metastases from extra-abdominal cancer - a population-based study. Flanagan M, Solon J, Chang KH, et al. https://doi.org/10.1016/j.ejso.2018.07.049. Eur J Surg Oncol. 2018;44:1811–1817. - PubMed
    1. National Comprehensive Cancer Network. (2021. National Comprehensive Cancer Network. Melanoma: cutaneous (version 2.2021) [ Mar; 2022 ]. 2021. https://www.nccn.org/professionals/physician_gls/pdf/cutaneous_melanoma.pdf https://www.nccn.org/professionals/physician_gls/pdf/cutaneous_melanoma.pdf - PubMed
    1. Patterns of failure and predictors of outcome in cutaneous malignant melanoma of the scalp. Terakedis BE, Anker CJ, Leachman SA, et al. J Am Acad Dermatol. 2014;70:435–442. - PubMed

Publication types

LinkOut - more resources