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Review
. 2023 Aug;50(8):1076-1080.
doi: 10.1111/1346-8138.16794. Epub 2023 Apr 5.

Palmoplantar pustulosis and pustulotic arthro-osteitis associated with multiple venous occlusion: A case report and literature review

Affiliations
Review

Palmoplantar pustulosis and pustulotic arthro-osteitis associated with multiple venous occlusion: A case report and literature review

Emi Inoue et al. J Dermatol. 2023 Aug.

Abstract

Pustulotic arthro-osteitis (PAO) is a rare chronic inflammatory arthropathy associated with palmoplantar pustulosis. The pathogenesis of PAO remains unclear. The most common musculoskeletal involvement in PAO is ossification of the sternoclavicular joints. A combination of parietal inflammation and hyperostosis-induced mechanical compression in this region is hypothesized to contribute to multiple venous thrombosis. Here, we present a 66-year-old man with PAO-associated multiple venous occlusion who was successfully treated with guselkumab. We also discuss its clinical manifestation and cause by reviewing the literature.

Keywords: case report; palmoplantar pustulosis; pustulotic arthro-osteitis; venous occlusion.

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References

REFERENCES

    1. Sonozaki H, Mitsui H, Miyanaga Y, Okitsu K, Igarashi M, Hayashi Y, et al. Clinical features of 53 cases with pustulotic arthro-osteitis. Ann Rheum Dis. 1981;40:547-53.
    1. Kishimoto M, Taniguchi Y, Tsuji S, Ishihara Y, Deshpande GA, Maeda K, et al. SAPHO syndrome and pustulotic arthro-osteitis. Mod Rheumatol. 2022;32:665-74.
    1. Hayem G, Bouchaud-Chabot A, Benali K, Roux S, Palazzo E, Silbermann-Hoffman O, et al. SAPHO syndrome: a long-term follow-up study of 120 cases. Semin Arthritis Rheum. 1999;29:159-71.
    1. Kawabata T, Morita Y, Nakatsuka A, Kagawa H, Kawashima M, Sei T, et al. Multiple venous thrombosis in SAPHO syndrome. Ann Rheum Dis. 2005;64:505-6.
    1. van Holsbeeck M, Martel W, Dequeker J, Favril A, Gielen J, Verschakelen J, et al. Soft tissue involvement, mediastinal pseudotumor, and venous thrombosis in pustulotic arthro-osteitis. Skeletal Radiol. 1989;18:1-8.

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