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Comment
. 2023 Apr 4;35(4):553-554.
doi: 10.1016/j.cmet.2023.03.012.

Metabolic set points of mammalian neurodevelopment

Fumi Suomi  1 , Anna Rappe  1 , Thomas G McWilliams  2
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Free article
Comment

Metabolic set points of mammalian neurodevelopment

Fumi Suomi et al. Cell Metab. .
Free article

Abstract

The human nervous system matures over a protracted developmental time frame relative to other species. What sets the pace of maturation has remained a mystery. In a recent publication in Science, Iwata et al. unearth critical contributions of mitochondrial metabolism in setting the pace of species-specific corticogenesis.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Mitochondria metabolism sets the species-specific tempo of neuronal development.
    Iwata R, Casimir P, Erkol E, Boubakar L, Planque M, Gallego López IM, Ditkowska M, Gaspariunaite V, Beckers S, Remans D, Vints K, Vandekeere A, Poovathingal S, Bird M, Vlaeminck I, Creemers E, Wierda K, Corthout N, Vermeersch P, Carpentier S, Davie K, Mazzone M, Gounko NV, Aerts S, Ghesquière B, Fendt SM, Vanderhaeghen P. Iwata R, et al. Science. 2023 Feb 10;379(6632):eabn4705. doi: 10.1126/science.abn4705. Epub 2023 Feb 10. Science. 2023. PMID: 36705539

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