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Review
. 2023 Jun;56(3):445-457.
doi: 10.1016/j.otc.2023.02.006. Epub 2023 Apr 3.

Introducing an Evidence-Based Approach to Wait-And-Scan Management of Sporadic Vestibular Schwannoma: Size Threshold Surveillance

Affiliations
Review

Introducing an Evidence-Based Approach to Wait-And-Scan Management of Sporadic Vestibular Schwannoma: Size Threshold Surveillance

John P Marinelli et al. Otolaryngol Clin North Am. 2023 Jun.

Abstract

The advent of MRI has led to more sporadic vestibular schwannomas diagnosed today than ever before. Despite the average patient being diagnosed in their sixth decade of life with a small tumor and minimal symptoms, population-based data demonstrate that more tumors per capita are treated today than ever before. Emerging natural history data justify either an upfront treatment approach or the "Size Threshold Surveillance" approach. Specifically, if the patient elects to pursue observation, then existing data support the tolerance of some growth during observation in appropriately selected patients up until a specific size threshold range (about 15 mm of CPA extension). The current article discusses the rationale behind a shift in the existing observation management approach, where initial detection of growth typically begets treatment, and outlines the application of a more flexible and nuanced approach based on existing evidence.

Keywords: Acoustic neuroma; Conservative management; Observation; Size threshold surveillance; Threshold observation; Treatment; Wait-and-scan.

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Conflict of interest statement

Conflicts of interest No authors have relevant conflicts of interest to disclose.