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Comment
. 2023 May;22(5):355.
doi: 10.1038/d41573-023-00053-5.

DENV inhibitor effective in non-human primates

Comment

DENV inhibitor effective in non-human primates

Sarah Crunkhorn. Nat Rev Drug Discov. 2023 May.
No abstract available

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Comment on

  • Blocking NS3-NS4B interaction inhibits dengue virus in non-human primates.
    Goethals O, Kaptein SJF, Kesteleyn B, Bonfanti JF, Van Wesenbeeck L, Bardiot D, Verschoor EJ, Verstrepen BE, Fagrouch Z, Putnak JR, Kiemel D, Ackaert O, Straetemans R, Lachau-Durand S, Geluykens P, Crabbe M, Thys K, Stoops B, Lenz O, Tambuyzer L, De Meyer S, Dallmeier K, McCracken MK, Gromowski GD, Rutvisuttinunt W, Jarman RG, Karasavvas N, Touret F, Querat G, de Lamballerie X, Chatel-Chaix L, Milligan GN, Beasley DWC, Bourne N, Barrett ADT, Marchand A, Jonckers THM, Raboisson P, Simmen K, Chaltin P, Bartenschlager R, Bogers WM, Neyts J, Van Loock M. Goethals O, et al. Nature. 2023 Mar;615(7953):678-686. doi: 10.1038/s41586-023-05790-6. Epub 2023 Mar 15. Nature. 2023. PMID: 36922586 Free PMC article.

References

    1. Goethals, O. et al. Blocking NS3–NS4B interaction inhibits dengue virus in non-human primates. Nature 615, 678–686 (2023) - PubMed - DOI - PMC

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