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This study uses data from the US Department of Veterans Affairs to assess whether SARS-CoV-2 remains associated with higher risk of death compared with seasonal influenza in fall-winter 2022-2023.
Conflict of Interest Disclosures: Dr Xie reported serving as a consultant (uncompensated) for Pfizer. Dr Al-Aly reported receiving consulting fees from Gilead Sciences and Tonix Pharmaceuticals and serving as a consultant (uncompensated) for Pfizer. No other disclosures were reported.
Figures
Figure.. Hazard Ratio, Death Rates, and Percentage…
Figure.. Hazard Ratio, Death Rates, and Percentage of Excess Deaths in COVID-19 Compared With Seasonal…
Figure.. Hazard Ratio, Death Rates, and Percentage of Excess Deaths in COVID-19 Compared With Seasonal Influenza
Comparison conducted in overall cohort by age (≤65, >65 years) and by COVID-19 vaccination status (unvaccinated, 1-2 doses of vaccine, and boosted), SARS-CoV-2 infection status (with primary SARS-CoV-2 infection and reinfection), and outpatient COVID-19 antiviral treatment (yes or no), compared with overall seasonal influenza. Outpatient COVID-19 antiviral treatment included nirmatrelvir-ritonavir, molnupiravir, or remdesivir.
Xie Y, Bowe B, Maddukuri G, Al-Aly Z. Comparative evaluation of clinical manifestations and risk of death in patients admitted to hospital with Covid-19 and seasonal influenza: cohort study. BMJ. 2020;371:m4677. doi:10.1136/bmj.m4677
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