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Clinical Trial
. 2023 May 1;141(5):1004-1006.
doi: 10.1097/AOG.0000000000005147. Epub 2023 Apr 5.

Levonorgestrel 52-mg Intrauterine Device Efficacy and Safety After More Than 8 Years of Use

Beatrice A Chen  1 , Thomas Kimble, Lisa H Harris, Jennifer L Kerns, Andrea I Olariu, Mitchell D Creinin
Affiliations
Free article
Clinical Trial

Levonorgestrel 52-mg Intrauterine Device Efficacy and Safety After More Than 8 Years of Use

Beatrice A Chen et al. Obstet Gynecol. .
Free article

Abstract

Funding source: Medicines360. The Sponsor, Medicines360, designed the study and oversaw its conduct, including funding the trial and providing all study product free of charge to participants.

Clinical trial registration: ClinicalTrials.gov, NCT00995150.

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References

    1. Creinin MD, Schreiber CA, Turok DK, Cwiak C, Chen BA, Olariu AI. Levonorgestrel 52 mg intrauterine system efficacy and safety through 8 years of use. Am J Obstet Gynecol 2022;227:871.e1–7. doi: 10.1016/j.ajog.2022.05.022 - DOI
    1. Jensen JT, Lukkari-Lax E, Schulze A, Wahdan Y, Serrani M, Kroll R. Contraceptive efficacy and safety of the 52-mg levonorgestrel intrauterine system for up to 8 years: findings from the Mirena Extension Trial. Am J Obstet Gynecol 2022;227:873.e1–12. doi: 10.1016/j.ajog.2022.09.007 - DOI
    1. Eisenberg DL, Schreiber CA, Turok DK, Teal SB, Westhoff CL, Creinin MD, et al. Three-year efficacy and safety of a new 52-mg levonorgestrel-releasing intrauterine system. Contraception 2015;92:10–6. doi: 10.1016/j.contraception.2015.04.006 - DOI
    1. Teal SB, Turok DK, Chen BA, Kimble T, Olariu AI, Creinin MD. Five-year contraceptive efficacy and safety of a levonorgestrel 52-mg intrauterine system. Obstet Gynecol 2019;133:63–70. doi: 10.1097/AOG.0000000000003034 - DOI
    1. Liletta prescribing information. Accessed February 6, 2023. https://www.rxabbvie.com/pdf/liletta_pi.pdf

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