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Review
. 2023 Jun;37(3):575-594.
doi: 10.1016/j.hoc.2023.02.009. Epub 2023 Apr 4.

Targeted Therapy for Non-Small Cell Lung Cancer: First Line and Beyond

Elliott Brea  1 , Julia Rotow  2
Affiliations
Review

Targeted Therapy for Non-Small Cell Lung Cancer: First Line and Beyond

Elliott Brea et al. Hematol Oncol Clin North Am. 2023 Jun.

Abstract

This article provides an updated review of the management of oncogene-driven non-small cell lung cancer. The use of targeted therapies for lung cancer driven by EGFR, ALK, ROS1, RET, NTRK, HER2, BRAF, MET, and KRAS are discussed, both in the first-line setting and in the setting of acquired resistance.

Keywords: Non–small cell lung cancer; Oncogenes; Resistance; Targeted therapy.

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