Safety of Alkalinization in CKD
- PMID: 37026750
- PMCID: PMC10103364
- DOI: 10.2215/CJN.0000000000000130
Safety of Alkalinization in CKD
Comment on
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Effect of Sodium Bicarbonate on Systolic Blood Pressure in CKD: A Systematic Review and Meta-Analysis.Clin J Am Soc Nephrol. 2023 Apr 1;18(4):435-445. doi: 10.2215/CJN.0000000000000119. Epub 2023 Mar 9. Clin J Am Soc Nephrol. 2023. PMID: 36758154 Free PMC article.
References
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- BiCARB Study Group. Clinical and cost-effectiveness of oral sodium bicarbonate therapy for older patients with chronic kidney disease and low-grade acidosis (BiCARB): a pragmatic randomised, double-blind, placebo-controlled trial. BMC Med. 2020;18(1):91. doi:10.1186/s12916-020-01542-9 - DOI - PMC - PubMed
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- Goraya N, Simoni J, Jo CH, Wesson DE. Treatment of metabolic acidosis in patients with stage 3 chronic kidney disease with fruits and vegetables or oral bicarbonate reduces urine angiotensinogen and preserves glomerular filtration rate. Kidney Int. 2014;86(5):1031–1038. doi:10.1038/ki.2014.83 - DOI - PubMed
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- Wesson DE, Mathur V, Tangri N, et al. . Long-term safety and efficacy of veverimer in patients with metabolic acidosis in chronic kidney disease: a multicentre, randomised, blinded, placebo-controlled, 40-week extension. Lancet. 2019;394(10196):396–406. doi:10.1016/S0140-6736(19)31388-1 - DOI - PubMed
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