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. 2023 May 23;329(20):1791-1792.
doi: 10.1001/jama.2023.5927.

Group A Streptococcal Meningitis With the M1UK Variant in the Netherlands

Affiliations

Group A Streptococcal Meningitis With the M1UK Variant in the Netherlands

Boas C L van der Putten et al. JAMA. .
No abstract available

Plain language summary

This study reports an epidemiological assessment of laboratory-confirmed group A streptococcal meningitis cases in the Netherlands using more than 40 years of national bacteriological surveillance data.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr van Sorge reported fees for service and consultancy with relation to bacterial meningitis surveillance for S pneumoniae, H influenzae, and N meningitidis paid directly to her institution from MSD (Merck) and GSK (GlaxoSmithKline); grants from Dutch Research Council Research (Aspasia, Vici), the NIH, and Amsterdam UMC Innovation outside the submitted work; holding a patent (WO 2013/020090 A3) licensed to the University of California San Diego on vaccine development against Streptococcus pyogenes; participating on the science advisory board of the ItsME foundation (no honorarium) and Rapua te me ngaro ka tau (paid to the institution; project facilitating strep A vaccine development for Aotearoa New Zealand); and owning personal stock in Genmab BV. No other disclosures were reported.

Figures

Figure.
Figure.. Number of Received Streptococcus pyogenes CSF Isolates With Proportion of emm1.0 Subtype, the Netherlands
Data for 2023 reported through March 13. CSF indicates cerebrospinal fluid.

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References

    1. Lucas MJ, Brouwer MC, Bovenkerk S, Man WK, van der Ende A, van de Beek D. Group A streptococcal meningitis in adults. J Infect. 2015;71(1):37-42. doi:10.1016/j.jinf.2015.01.008 - DOI - PubMed
    1. Kjærgaard N, Bodilsen J, Justesen US, et al. ; DASGIB Study Group . Community-acquired meningitis caused by beta-haemolytic streptococci in adults: a nationwide population-based cohort study. Eur J Clin Microbiol Infect Dis. 2019;38(12):2305-2310. doi:10.1007/s10096-019-03678-w - DOI - PubMed
    1. Holdstock V, Twynam-Perkins J, Bradnock T, et al. . National case series of group A streptococcus pleural empyema in children: clinical and microbiological features. Lancet Infect Dis. 2023;23(2):154-156. doi:10.1016/S1473-3099(23)00008-7 - DOI - PubMed
    1. van Kempen EB, Bruijning-Verhagen PCJ, Borensztajn D, et al. . Increase in invasive group A streptococcal infections in children in the Netherlands: a survey among 7 hospitals in 2022. Pediatr Infect Dis J. 2023;42(4):e122-e124. doi:10.1097/INF.0000000000003810 - DOI - PubMed
    1. CDC Streptococcus laboratory. Resources and protocols. Updated July 23, 2021. Accessed April 1, 2023. https://www.cdc.gov/streplab/groupa-strep/resources.html

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