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Review
. 2023 May 1;45(4):209-212.
doi: 10.1097/MPH.0000000000002659. Epub 2023 Mar 16.

Skin Lesions as a Presenting Feature of Dimorphic T-Lymphoblastic Leukemia in an Adolescent Male

Stacy Chapman  1 , Muhamad Almiski  2 , Daniel Marko  2 , Debora Sekiguchi  3 , A J Dawson  4 , Richard Keijzer  3 , Jonathan Fromm  5 , Sara J Israels  1
Affiliations
Review

Skin Lesions as a Presenting Feature of Dimorphic T-Lymphoblastic Leukemia in an Adolescent Male

Stacy Chapman et al. J Pediatr Hematol Oncol. .

Abstract

Cutaneous involvement is rare in acute lymphoblastic leukemia/lymphoma, particularly within the T-cell lineage. Review of the literature for cutaneous involvement in T-cell lymphoblastic lymphoma/leukemia identifies mostly case reports, with the majority of cases involving adults. We describe an adolescent male presenting with cervical lymphadenopathy and skin lesions leading to a diagnosis of early T-cell precursor lymphoblastic leukemia. Unique to this case is the age of the patient, presence of a dimorphic blast population, and the skin lesions preceding other signs of disease by at least 1 month.

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Conflict of interest statement

A.J.D. is a member of the Pfizer Cytogenetics Advisory Board. The remaining authors declare no conflict of interest.

References

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