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Review
. 2023 May:245:154451.
doi: 10.1016/j.prp.2023.154451. Epub 2023 Apr 5.

A review on the role of NCK1 Antisense RNA 1 (NCK1-AS1) in diverse disorders

Mohammad Taheri  1 , Arian Askari  2 , Kimia Behzad Moghadam  3 , Bashdar Mahmud Hussen  4 , Soudeh Ghafouri-Fard  5 , Arda Kiani  6
Affiliations
Free article
Review

A review on the role of NCK1 Antisense RNA 1 (NCK1-AS1) in diverse disorders

Mohammad Taheri et al. Pathol Res Pract. 2023 May.
Free article

Abstract

NCK1 Antisense RNA 1 (NCK1-AS1), alternatively named as NCK1-DT, is a long non-coding RNA (lncRNA) with important roles in the carcinogenesis. Multiple studies verified its oncogenic role in different types of cancer, including gastric cancer, non-small cell lung cancer, glioma, prostate cancer and cervical cancer. NCK1-AS1 functions as a sponge for several microRNAs, including miR-137, miR-22-3p, miR-526b-5p, miR-512-5p, miR-138-2-3p and miR-6857. In this review we present an outline of NCK1-AS1 function in malignant conditions as well as atherosclerosis.

Keywords: Cancer; LncRNA; MicroRNAs; NCK1-AS1.

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Conflict of interest statement

Declaration of Competing Interest The authors declare they have no conflict of interest.

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