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Review
. 2023 May;41(2):359-369.
doi: 10.1016/j.ncl.2023.01.003. Epub 2023 Feb 20.

Sex-Specific Neurocognitive Impairment

Sharlet A Anderson  1 , Maria A Rossetti  2
Affiliations
Review

Sex-Specific Neurocognitive Impairment

Sharlet A Anderson et al. Neurol Clin. 2023 May.

Abstract

This article explores sex-specific neurocognitive impairment. It first defines relevant terms such as gender and sex. Next, it describes the nature of the problem including under-representation of women and other gender and sexual minorities in neuroscience research, including cognitive studies. A biopsychosocial framework is employed to account for structural and social determinants of health in sex/gender-specific neurocognitive impairment. Issues in assessment including the use of gender/sex-specific normative data are also discussed. Lastly, the article covers the current state of research as it relates to sex/gender-specific neurocognitive impairment across a range of medical conditions including neurodegenerative diseases and coronavirus disease-2019.

Keywords: Cognition; Gender; Intersectionality; Neurocognitive disorders; Neurofeminism; Sex.

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