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Review
. 2023 Apr 8;6(1):381.
doi: 10.1038/s42003-023-04635-2.

Uncovering biology by single-cell proteomics

M Shahid Mansuri  1 , Kenneth Williams  1 , Angus C Nairn  2
Affiliations
Review

Uncovering biology by single-cell proteomics

M Shahid Mansuri et al. Commun Biol. .

Abstract

Recent technological advances have opened the door to single-cell proteomics that can answer key biological questions regarding how protein expression, post-translational modifications, and protein interactions dictate cell state in health and disease.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1. Single-cell proteomics methods.
a Schematic of a single unit of a single-cell integrated proteomics chip (SciProChip) and streamlined workflow for nano-proteomics used by Gebreyesus et al. b A nanopore device used by Brinkerhoff et al. to read DNA–protein conjugates with single amino acid resolution.
See this image and copyright information in PMC

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