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Editorial
. 2023 Mar 31;12(3):452-455.
doi: 10.21037/tcr-22-2605. Epub 2023 Feb 20.

Notes on the morphological features of cotyledonary dissecting leiomyoma, which is rare in clinical practice

Saya Tamura  1 , Takuma Hayashi  2   3 , Nobuo Yaegashi  3   4 , Kaoru Abiko  1 , Ikuo Konishi  1   3
Affiliations
Editorial

Notes on the morphological features of cotyledonary dissecting leiomyoma, which is rare in clinical practice

Saya Tamura et al. Transl Cancer Res. .
No abstract available

Keywords: Cotyledonoid dissecting leiomyoma; leiomyoma; leiomyosarcoma; uterine mesenchymal tumor.

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-22-2605/coif). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Morphological characteristics of a cotyledonoid dissecting leiomyoma observed on MRI and histopathological examination. (A) Results of MRI. The T2W1 image shows a continuous, low-to-high-intensity mass lesion originating within the right muscle layer of the uterine corpus, extending outward into the uterus. The mass (encircled by a dotted line) is present between the round ligament (white arrow) and uterine artery and is enclosed by a membrane. The right ovary (white arrow) present superior to the mass is normal. The images suggest that the mass may be a degenerative uterine leiomyoma growing from within the myometrium into the broad ligament. The leiomyoma measures approximately 20 mm in size on the posterior wall of the uterine fundus. No lesions are seen in the ovaries. Significant lymphadenopathy or ascites is absent. (B) Results of histopathological examination. A soft mass approximately 120 mm in size is seen protruding from the uterine serosal surface. The cut surface of the mass is grayish white and multinodular and demonstrates a proliferation of smooth muscle cells having an island-like/alveolar-like morphology with edematous stroma. Marked infiltration of these smooth muscle cells into the uterine smooth muscle layer is observed. There is also evidence of infiltration of some proliferating smooth muscle cells into the blood vessels. No severe nuclear atypia or mitotic cells are observed. On the basis of these findings, a diagnosis of cotyledonoid dissecting leiomyoma can be considered. Surgical pathological examination reveals no malignant findings in cervical and fallopian tube tissues. Upper panel: magnification ×10; lower panel: magnification ×40. (C) Illustration of the gross findings of the patient’s cotyledonoid dissecting leiomyoma. MRI, magnetic resonance imaging; H&E, hematoxylin and eosin; CDL, cotyledonoid dissecting leiomyoma.
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References

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