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. 2023 Mar 1;13(5):2979.
doi: 10.3390/app13052979. Epub 2023 Feb 25.

Laryngeal Imaging Study of Glottal Attack/Offset Time in Adductor Spasmodic Dysphonia during Connected Speech

Maryam Naghibolhosseini  1 , Stephanie R C Zacharias  2   3 , Sarah Zenas  4 , Farrah Levesque  5 , Dimitar D Deliyski  1
Affiliations

Laryngeal Imaging Study of Glottal Attack/Offset Time in Adductor Spasmodic Dysphonia during Connected Speech

Maryam Naghibolhosseini et al. Appl Sci (Basel). .

Abstract

Adductor spasmodic dysphonia (AdSD) disrupts laryngeal muscle control during speech and, therefore, affects the onset and offset of phonation. In this study, the goal is to use laryngeal high-speed videoendoscopy (HSV) to measure the glottal attack time (GAT) and glottal offset time (GOT) during connected speech for normophonic (vocally normal) and AdSD voices. A monochrome HSV system was used to record readings of six CAPE-V sentences and part of the "Rainbow Passage" from the participants. Three raters visually analyzed the HSV data using a playback software to measure the GAT and GOT. The results show that the GAT was greater in the AdSD group than in the normophonic group; however, the clinical significance of the amount of this difference needs to be studied further. More variability was observed in both GATs and GOTs of the disorder group. Additionally, the GAT and GOT time series were found to be nonstationary for the AdSD group while they were stationary for the normophonic voices. This study shows that the GAT and GOT measures can be potentially used as objective markers to characterize AdSD. The findings will potentially help in the development of standardized measures for voice evaluation and the accurate diagnosis of AdSD.

Keywords: adductor spasmodic dysphonia; connected speech; glottal attack time; glottal offset time; high-speed videoendoscopy; laryngeal imaging.

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Conflict of interest statement

Conflicts of Interest: The authors declare no conflict of interest.

Figures

Figure 1.
Figure 1.
GAT bar graph for normophonic and AdSD voices. The central horizontal line and the bottom and top edges of the boxes indicate the median, 25th, and 75th percentiles, respectively. The whiskers are indicative of extreme data points after the outlier removal. The individual stars show the outliers.
Figure 2.
Figure 2.
GOT bar graph for normophonic and AdSD voices. The central horizontal line and the bottom and top edges of the boxes indicate the median, 25th, and 75th percentiles, respectively. The whiskers are indicative of extreme data points after the outlier removal. The individual stars show the outliers.
Figure 3.
Figure 3.
GAT distribution (in ms) for the true vocal folds (bottom panel) and false vocal folds (top panel).
Figure 4.
Figure 4.
GOT distribution (in ms) for the true vocal folds (bottom panel) and false vocal folds (top panel).
Figure 5.
Figure 5.
GAT values (in ms) for different vocalizations (x-axis) for the normophonic voices (panel (a)) and AdSD (panel (b)). The subject IDs are shown in the legend.
See this image and copyright information in PMC

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