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Case Reports
. 2023 Mar 31:2023:5670538.
doi: 10.1155/2023/5670538. eCollection 2023.

Intravitreal Dexamethasone Implant in Autoimmune Retinopathy

Fernando Longhi Bordin  1 , Carolina da Silva Mengue  1 , Manuel Augusto Pereira Vilela  2
Affiliations
Case Reports

Intravitreal Dexamethasone Implant in Autoimmune Retinopathy

Fernando Longhi Bordin et al. Case Rep Ophthalmol Med. .

Abstract

Purpose: To describe the results of an intravitreal dexamethasone implant in managing autoimmune retinopathy (AIR).

Methods: Two patients affected by AIR underwent intravitreal dexamethasone implantation and were followed by ocular coherence tomography, visual fields, and electroretinography.

Results: The patients showed an interruption of the functional losses and remained stable with semestral injections.

Conclusion: AIR is a complex condition with no standard treatment. The use of dexamethasone could be a valid option.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Retinography (a, c) showing optic disc pallor and arteriolar attenuation. The Goldmann visual field (b, d) showed bilateral constriction and central scotoma.
Figure 2
Figure 2
Retinography (a) and FA (c) showed important arterial narrowing. IVFA (b) showed no alterations. Humphrey visual field (d) showed diminished bilateral nasal sensitivity. Optic disc and macula OCT (e, f). ERG (g) showed diminished bilateral responses.
See this image and copyright information in PMC

References

    1. Sawyer R. A., Selhorst J. B., Zimmerman L. E., Hoyt W. F. Blindness caused by photoreceptor degeneration as a remote effect of cancer. American Journal of Ophthalmology . 1976;81(5):606–613. doi: 10.1016/0002-9394(76)90125-2. - DOI - PubMed
    1. Dutta Majumder P., Marchese A., Pichi F., Garg I., Agarwal A. An update on autoimmune retinopathy. Indian Journal of Ophthalmology . 2020;68(9):1829–1837. doi: 10.4103/ijo.IJO_786_20. - DOI - PMC - PubMed
    1. Pawestri A. R., Arjkongharn N., Suvannaboon R., et al. Autoantibody profiles and clinical association in Thai patients with autoimmune retinopathy. Nature Scientifc Reports . 2021;11(1, article 15047) doi: 10.1038/s41598-021-94377-0. - DOI - PMC - PubMed
    1. Sem H. N., Grange L., Marib Akanda B. S., Fox A. Autoimmune retinopathy: current concepts and practices (an American Ophthalmological Society thesis) Transactions of the American Ophthalmological Society . 2017;115 - PMC - PubMed
    1. Heckenlively J. R., Ferreyra H. A. Autoimmune retinopathy: a review and summary. Seminars in Immunopathology . 2008;30(2):127–134. doi: 10.1007/s00281-008-0114-7. - DOI - PubMed

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