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. 2023 Jun;54(2):1309-1314.
doi: 10.1007/s42770-023-00963-x. Epub 2023 Apr 10.

A novel recombinant porcine sapovirus infection in piglets with diarrhea in Shandong Province, China, 2022

Ran Wei  1 , Rui Shang  2 , Kaihui Cheng  3 , Song Wang  4 , Jiaqiang Wu  2   3 , Zhijun Yu  5
Affiliations

A novel recombinant porcine sapovirus infection in piglets with diarrhea in Shandong Province, China, 2022

Ran Wei et al. Braz J Microbiol. 2023 Jun.

Abstract

Sapporo virus (SaV) is an emerging enteric virus causing acute gastroenteritis in animals. Here, we found a novel porcine SaV (PoSaV) strain (named SD2202) from the piglets with diarrhea in China in 2022. The highest nucleotide homology of SD2202 with other PoSaV strains is only 90.67%, and there are four amino acids insertion in the viral capsid protein and minor structural protein compared to other PoSaV; furthermore, we found that SD2202 belongs to a new GIII genogroup clade (GIII-6 clade). Interestingly, we found that SD2202 may be an intra-genogroup recombinant strain. Taken together, we found a novel PoSaV implicated in the piglet diarrhea epidemic and emphasized the importance of continuous surveillance of PoSaV.

Keywords: Emerging infectious disease; Gene recombination; Sapovirus; Swine.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Sequence alignment was performed using the ClustalW method based on genome (a) and RDRP (b). Red circles indicate PoSaV strains detected in this study
Fig. 2
Fig. 2
Phylogenetic tree based on the VP1 nucleotide sequences of SaV
Fig. 3
Fig. 3
Recombination analysis of the nucleotide sequence of SD2202 using SimPlot software. Red and yellow mark the recombined parental strains on each tree
See this image and copyright information in PMC

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