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Review
. 2023 Jul-Aug;15(4):e1888.
doi: 10.1002/wnan.1888. Epub 2023 Apr 10.

Copper-based nanoparticles against microbial infections

Xiumin Li  1   2 , Yalin Cong  2   3 , Muhammad Ovais  3 , Mateus Borba Cardoso  4 , Saima Hameed  2 , Rui Chen  5 , Mingli Chen  1 , Liming Wang  2
Affiliations
Review

Copper-based nanoparticles against microbial infections

Xiumin Li et al. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2023 Jul-Aug.

Abstract

Drug-resistant bacteria and highly infectious viruses are among the major global threats affecting the human health. There is an immediate need for novel strategies to tackle this challenge. Copper-based nanoparticles (CBNPs) have exhibited a broad antimicrobial capacity and are receiving increasing attention in this context. In this review, we describe the functionalization of CBNPs, elucidate their antibacterial and antiviral activity as well as applications, and briefly review their toxicity, biodistribution, and persistence. The limitations of the current study and potential solutions are also shortly discussed. The review will guide the rational design of functional nanomaterials for antimicrobial application. This article is categorized under: Therapeutic Approaches and Drug Discovery > Nanomedicine for Infectious Disease.

Keywords: antimicrobial activity; bacteria; copper-based nanoparticles; microbial infection; virus.

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References

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