Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Apr 10;24(1):276.
doi: 10.1186/s12891-023-06341-w.

Efficacy of percutaneous kyphoplasty on vertebral compression fractures with different bone mineral densities: a retrospective study

Chen Ge #  1 , Zhe Chen #  2 , Peng Cao  2
Affiliations

Efficacy of percutaneous kyphoplasty on vertebral compression fractures with different bone mineral densities: a retrospective study

Chen Ge et al. BMC Musculoskelet Disord. .

Abstract

Background: This study was performed to investigate the clinical efficacy of percutaneous kyphoplasty (PKP) for vertebral compression fractures with different bone mineral densities (BMD).

Methods: We performed a retrospective analysis of 232 patients with single-segment vertebral compression fractures who underwent PKP. Patients were divided into the normal BMD, osteopenia, and osteoporosis groups according to their average lumbar BMD before surgery. The visual analog scale (VAS) was used to compare differences in pain relief before and after surgery in each group. Corrections of the wedge angle and kyphotic angle before and after surgery were observed using anteroposterior and lateral radiographs and compared among the groups, as was the incidence of bone cement leakage.

Results: Patients were followed up for 6-12 months, with an average follow-up time of 9.12 ± 1.68 months. The VAS score, wedge angle, and kyphotic angle of the three groups of patients decreased significantly at the end of the follow-up (P < 0.05). The changes in VAS score and wedge angle correction in the osteoporosis group were significantly larger than those in the normal BMD and osteopenia groups (P < 0.05). There were no significant differences among the three groups in terms of kyphotic angle correction or bone cement leakage rates (P > 0.05).

Conclusions: PKP has a positive effect on vertebral compression fractures with different BMD, and is especially suitable for osteoporotic vertebral compression fractures.

Keywords: Bone mineral density; Kyphotic angle; Percutaneous kyphoplasty; Vertebral compression fractures; Wedge angle.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interest.

Similar articles

See all similar articles

Cited by

References

    1. Curtis EM, Moon RJ, Dennison EM, Harvey NC, Cooper C. Recent advances in the pathogenesis and treatment of osteoporosis. Clin Med. 2016;16(4):360–4. doi: 10.7861/clinmedicine.16-4-360. - DOI - PMC - PubMed
    1. Langella F, Balestrino A, Damilano M, Cecchinato R, Biber Z, Paoletta M, Iolascon G, Lamartina C, Peretti GM, Berjano P. The aging spine: the effect of vertebral fragility fracture on sagittal alignment. Arch Osteoporos. 2021;16(1):109. doi: 10.1007/s11657-021-00975-w. - DOI - PubMed
    1. Long Y, Yi W, Yang D. Advances in Vertebral Augmentation Systems for Osteoporotic Vertebral Compression Fractures. Pain Res Manag 2020, 2020:3947368. - PMC - PubMed
    1. Karmakar A, Acharya S, Biswas D, Sau A. Evaluation of Percutaneous Vertebroplasty for Management of Symptomatic Osteoporotic Compression fracture. J Clin Diagn Res. 2017;11(8):Rc07–rc10. - PMC - PubMed
    1. Nazrun AS, Tzar MN, Mokhtar SA, Mohamed IN. A systematic review of the outcomes of osteoporotic fracture patients after hospital discharge: morbidity, subsequent fractures, and mortality. Ther Clin Risk Manag. 2014;10:937–48. - PMC - PubMed

MeSH terms