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Review
. 2023 Mar;31(1):76-83.
doi: 10.5455/aim.2023.31.76-83.

Incidence and Comparison of Suicide in Various Phases of the Menstrual Cycle: a Systematic Review and Meta-analysis

Yara A Alnashwan  1 , Ahmed Mustafa Rashid  2 , Syed Sarmad Javaid  2 , Magdy A Kharoshah  3 , M Arun  4 , Haneil Larson Dsouza  5   6 , Alok Atreya  7 , Ritesh George Menezes  1
Affiliations
Review

Incidence and Comparison of Suicide in Various Phases of the Menstrual Cycle: a Systematic Review and Meta-analysis

Yara A Alnashwan et al. Acta Inform Med. 2023 Mar.

Abstract

Background: Suicide is a global health concern. There are reproductive health-related factors that are responsible for increasing the risk of female suicide. There are a number of studies examining the association between suicide and the menstrual cycle, but still, there are no conclusive findings.

Aim: We aimed to pool data from all the studies reporting data on suicides and the menstrual cycle phase to report the following outcomes: incidence of suicidal deaths in the menstrual, secretory, and proliferative phases, and to find out whether the burden of suicide in the menstrual phase in particular, was more at a young age (18-35 years) or middle age (36-50years).

Methods: The PubMed database was extensively searched from inception till 12th April 2022. The data for the number of events occurring for each outcome were pooled using random-effects model and forest plots were created.

Results: Five articles were shortlisted for inclusion in our analysis. Incidence of suicide in the secretory phase was highest at 45.2% [95% CI, 0.367-0.537]. The incidence of suicide, when occurring in the menstrual phase, was reported to be 68.4% (95 CI, 0.317-1.052) and 31.6% (95 CI, -0.052.3-0.68) for young-aged and middle-aged victims, respectively.

Conclusion: Our results demonstrate that the menstrual phase has a lower risk of mortality due to suicide when compared to the other two phases of the menstrual cycle. Nevertheless, when suicide occurred in the menstrual phase, the incidence of suicide among the younger age-group was higher than for those in the middle age-group.

Keywords: Menstruation; Suicide; Uterine histopathology; Women’s health issues.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1.
Figure 1.. PRISMA flowchart
Figure 2.
Figure 2.. Summary of the results of the meta-analysis
Supplementary Table S1.
Supplementary Table S1.. Search string used for data extraction from inception till 12th April, 2022
Supplementary Table S2.
Supplementary Table S2.. Quality assessment
Figure S1.
Figure S1.. The incidence of deaths due to suicide in the menstrual phase
Figure S2.
Figure S2.. The incidence of deaths due to suicide in the secretory phase
Figure S3.
Figure S3.. The incidence of deaths due to suicide in the proliferative phase
Figure S4.
Figure S4.. Forest plot showing risk ratio of death between menstrual phase and secretory phase
Figure S5.
Figure S5.. The incidence of suicide at a middle age during the menstrual phase
Figure S6.
Figure S6.. The incidence of suicide at a young age during the menstrual phase
Figure S7.
Figure S7.. Forest plot showing risk ratio of death between menstrual phase and proliferative phase
See this image and copyright information in PMC

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References

    1. Vijayakumar L. Suicide in women. Indian J Psychiatry. 2015;57:S233–8. - PMC - PubMed
    1. Beautrais AL. Suicide in Asia. Crisis. 2006;27:55–7. - PubMed
    1. Turecki G, Brent DA, Gunnell D, O’Connor RC, Oquendo MA, Pirkis J, et al. Suicide and suicide risk. Nat Rev Dis Primers. 2019;5:74. - PubMed
    1. Turecki G, Brent DA. Suicide and suicidal behaviour. Lancet. 2016;387:1227–39. - PMC - PubMed
    1. Women and Suicide. Part 2. Risk and Protective Factors. Centre for Suicide Prevention. SIEC

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