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. 2023 Apr 4:18:459-468.
doi: 10.2147/COPD.S400213. eCollection 2023.

Prevalence and Risk Factors for COPD in an Urbanizing Rural Area in Western China: A Cross-Sectional Study

Xiaolong Zhang #  1 , Zhiyin Lei #  2 , Ying Wu  3 , Yuanyuan Song  4 , Xiaoling Wu  3   5 , Bo Yang  2 , Jianmei Fan  2 , Shixu Feng  2 , Liping Wu  2 , Lingyan Li  2 , Qin Dai  2 , Zhen Zeng  2 , Mei Feng  3 , Tingting Zhang  3
Affiliations

Prevalence and Risk Factors for COPD in an Urbanizing Rural Area in Western China: A Cross-Sectional Study

Xiaolong Zhang et al. Int J Chron Obstruct Pulmon Dis. .

Abstract

Purpose: To investigate the prevalence and risk factors for chronic obstructive pulmonary disease (COPD) in a rural area in western China with severe air pollution.

Patients and methods: 10% of local residents aged 40 years and above were included using a convenience sampling method. This was a cross-sectional study. A self-designed questionnaire was used to collect participants' demographic data. The screening program was comprised of two steps: First, a portable electronic spirometer was used for COPD screening. Those participants with FEV1/FVC ratio <0.7 were then referred to a confirmatory pulmonary function (PF) test. COPD was confirmed according to the 2020 Global Initiative for Chronic Obstructive Lung Disease criteria.

Results: A total of 4577 participants aged 40 years old or above were included in the final analysis. Examination with a mobile spirometer identified 1159 individuals for confirmatory testing; after that, of the 1159 individuals, 889 were diagnosed with COPD by the confirmatory PF test. The prevalence of COPD among the target group was 19.4%. Older age, male sex (odds ratio [OR] = 1.537, 95% confidence interval [CI] 1.246-1.894), smoking history (OR = 1.338, 95% CI 1.069-1.675), family history of respiratory disease (OR = 1.625, 95% CI 1.350-1.957), education level (OR = 0.735, 95% CI 0.617-0.876), overweight (OR = 0.614, 95% CI 0.517-0.730) and obesity (OR = 0.572, 95% CI 0.449-0.721) were identified as independent factors associated with COPD. The screening program helped earlier detection of COPD in 719 participants.

Conclusion: COPD was highly prevalent in the rural area studied. Rural residents who were older, current or ever-smokers, male and those who had a lower education level were more vulnerable to developing COPD. The COPD screening program may be helpful for earlier disease detection in rural health-care settings.

Keywords: chronic obstructive pulmonary disease; prevalence; primary care; pulmonary function test; risk factors.

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Conflict of interest statement

The authors report no conflicts of interest in this work.

Figures

Figure 1
Figure 1
The process of subject inclusion.
Figure 2
Figure 2
The association between risk factors and COPD via logistic regression modeling.
See this image and copyright information in PMC

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