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. 2023 Jul;41(4):492-500.
doi: 10.1007/s00774-023-01419-w. Epub 2023 Apr 11.

Bone-specific physical activity questionnaire-derived skeletal loading score predicts bone geometry, density, and strength indices: a cross-sectional study

Benjamin K Weeks  1   2 , Amy T Harding  3 , Steven L Watson  3   4 , Conor Lambert  3   4 , Rossana C Nogueira  3 , Rebecca Hirsch  3   5 , Timo Rantalainen  6 , Jayde Collier  3 , Belinda R Beck  3   7   8
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Bone-specific physical activity questionnaire-derived skeletal loading score predicts bone geometry, density, and strength indices: a cross-sectional study

Benjamin K Weeks et al. J Bone Miner Metab. 2023 Jul.

Abstract

Introduction: The bone-specific physical activity questionnaire (BPAQ) provides a bone-relevant index of physical activity participation according to the mechanical loads experienced across the life span.

Materials and methods: We aimed to examine relationships between historical bone-relevant physical activity and pQCT-derived parameters of bone strength. We recruited 532 healthy volunteers (277 males, 255 females) across a broad age range (4-97 years). Peripheral quantitative computed tomography (XCT-3000, Stratec, Germany) was used to examine volumetric bone density, area, and strength indices of the non-dominant tibia and radius. Exercise loading history from birth was determined using the past BPAQ (pBPAQ) score. Pearson correlation analysis was used to examine relationships between pBPAQ scores and pQCT parameters.

Results: Independent of sex, pBPAQ scores were associated with total density at the 38% and 66% tibial sites and the 66% radial site (r = 0.145-0.261, p ˂ 0.05), total area at the 38% tibial site and 4% and 66% radial sites (r = 0.129-0.156, p ˂ 0.05), and strength indices at all measured sites (r = 0.123-0.234, p < 0.05).

Conclusion: We conclude that, independent of sex, historical bone-relevant physical activity is associated with pQCT-derived indices of bone strength, indicating that pBPAQ captures the characteristics of bone loading history that are likely to be relevant adaptive stimuli. A larger sample is required to examine the influence of age on this relationship.

Keywords: Bone geometry; Bone strength; Exercise; Physical activity questionnaire; pQCT.

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References

    1. Rubin CT (1984) Skeletal strain and the functional significance of bone architecture. Calcif Tissue Int 36:S11-18 - DOI - PubMed
    1. Turner CH, Owan I, Takano Y (1995) Mechanotransduction in bone: Role of strain rate. Am J Physiol 269:E438-442 - PubMed
    1. Weeks BK, Beck BR (2008) Eight months of regular in-school jumping improves indices of bone strength in adolescent boys and girls: Results of the POWER PE study. J Bone Miner Res 23:1002–1011 - DOI - PubMed
    1. Weeks BK, Beck BR (2012) Are bone and muscle changes from POWER PE, an 8-month in-school jumping intervention, maintained at three years? PLoS ONE 7:e39133 - DOI - PubMed - PMC
    1. Robling AG, Hinant FM, Burr DB, Turner CH (2002) Shorter, more frequent mechanical loading sessions enhance bone mass. Med Sci Sports Exerc 34:196–202 - DOI - PubMed

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