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. 2023 Jun;20(6):367-368.
doi: 10.1038/s41569-023-00871-5.

Improving the cardiovascular health care of transgender and non-binary persons

Arjee Restar  1   2 , Carl G Streed Jr  3   4   5
Affiliations

Improving the cardiovascular health care of transgender and non-binary persons

Arjee Restar et al. Nat Rev Cardiol. 2023 Jun.

Abstract

Research consistently shows that gender-affirming practices improve markers of cardiovascular health. Consequently, the focus of the management of the cardiovascular health of transgender and non-binary populations should not be on their hormone therapies and surgical histories, but should instead be rooted in the routine screening of cardiovascular risk factors.

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Conflict of interest statement

Competing interests

C.G.S.Jr has received consulting fees from EverlyWell and the Texas Health Institute. A.R. declares no competing interests.

Figures

Fig. 1 |
Fig. 1 |. Social determinants of health relevant to the cardiovascular health of the trans population.
Multilevel stressors exist in every domain of social determinants of health for transgender and non-binary persons (here referred to collectively as trans persons), which, together with gender-affirmative interventions, can influence biological pathways to trigger chronic inflammation and contribute to the development and progression of cardiovascular disease.
See this image and copyright information in PMC

References

    1. Streed CG Jr et al. Assessing and addressing cardiovascular health in people who are transgender and gender diverse: a scientific statement from the American Heart Association. Circulation 144, e136–e148 (2021). - PMC - PubMed
    1. Lloyd-Jones DM et al. Life’s essential 8: updating and enhancing the American Heart Association’s construct of cardiovascular health: a presidential advisory from the American Heart Association. Circulation 146, e18–e43 (2022). - PMC - PubMed
    1. Arrington-Sanders R et al. Assessing and addressing the risk of venous thromboembolism across the spectrum of gender affirming care: a review. Endocr. Pract 29, 272–278 (2023). - PMC - PubMed
    1. Restar A et al. Gender affirming hormone therapy dosing behaviors among transgender and nonbinary adults. Humanit. Soc. Sci. Commun 9, 304 (2022). - PMC - PubMed
    1. Powell-Wiley TM et al. Social determinants of cardiovascular disease. Circ. Res 130, 782–799 (2022). - PMC - PubMed

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