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. 2023 Jun;201(6):1125-1128.
doi: 10.1111/bjh.18807. Epub 2023 Apr 12.

Improved outcomes in patients with chronic lymphocytic leukaemia infected during the omicron BA.5 subvariant surge

Yotam Bronstein  1 , Shai Levi  1 , Yair Herishanu  1   2
Affiliations

Improved outcomes in patients with chronic lymphocytic leukaemia infected during the omicron BA.5 subvariant surge

Yotam Bronstein et al. Br J Haematol. 2023 Jun.

Abstract

Patients with chronic lymphocytic leukaemia (CLL) infected with SARS-CoV-2 are at increased risk of severe COVID-19 and death. The outcomes of CLL patients with COVID-19 during the omicron subvariants and in particular with BA.5 are not fully elucidated. Here, we report the outcomes of 128 CLL patients diagnosed with COVID-19 from December 2021 through November 2022. The hospitalization and 30-day mortality rates were 26.6% (n = 34) and 4.7% (n = 6), respectively. Both hospitalizations and mortality were lower during the outbreaks of the BA.2 and BA.5 subvariants (17.2%, 0% vs. 15.2%, 0%, respectively) compared with the period dominated by the BA.1 subvariant (41.5%, 11.3%).

Keywords: BA.5; CLL; COVID-19; Omicron; SARS-CoV-2.

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References

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