Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Jun;86(6):e156-e157.
doi: 10.1016/j.jinf.2023.04.002. Epub 2023 Apr 11.

Low levels of humoral response to monkeypox virus-specific antigens in healthy individuals

Kehong Zhang  1 , Yuzhong Xu  2 , Huihua Zhang  3 , Huanwei Zheng  4 , Xinchun Chen  5 , Dachuan Lin  6
Affiliations
Comment

Low levels of humoral response to monkeypox virus-specific antigens in healthy individuals

Kehong Zhang et al. J Infect. 2023 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest We attest that there are no conflicts of interest related to the research or the manuscript.

Figures

Fig. 1
Fig. 1
The results of the enzyme-linked immunosorbent assay (ELISA). ELISA was used to determine MPXV-specific immunoglobulin G (IgG) levels, represented as optical density (OD) values at 450 nm (OD450). The data includes OD450 values (log2 transformed) for three targets, comparing two birth cohorts: the post-1981 and pre-1971 groups. The median value is indicated by the bar in the graph. Statistical significance, determined by the Wilcoxon test, is denoted by p ≤ 0.05.
See this image and copyright information in PMC

Comment on

References

    1. Moschese D., Pozza G., Giacomelli A., Mileto D., Cossu M., Beltrami M., et al. Natural history of human Monkeypox in individuals attending a sexual health clinic in Milan, Italy. J Infect. 2023;86(1):e18–e20. doi: 10.1016/j.jinf.2022.08.019. - DOI - PMC - PubMed
    1. Raccagni A., Candela C., Mileto D., Bruzzesi E., Canetti D., Bertoni C., et al. Breakthrough monkeypox infection among individuals previously immunized with smallpox or monkeypox vaccination. J Infect. 2023;86(2):154–225. doi: 10.1016/j.jinf.2022.12.001. - DOI - PMC - PubMed
    1. Edghill-Smith Y., Golding H., Manischewitz J., King L., Scott D., Bray M., et al. Smallpox vaccine-induced antibodies are necessary and sufficient for protection against monkeypox virus. Nat Med. 2005;11(7):740–747. doi: 10.1038/nm1261. - DOI - PubMed
    1. Gong Q., Wang C., Chuai X., Chiu S. Monkeypox virus: a re-emergent threat to humans. Virol Sin. 2022;37(4):477–482. doi: 10.1016/j.virs.2022.07.006. - DOI - PMC - PubMed
    1. Fenner F., Breman J.G., Organization W.H. World Health Organization; 1978. Report on a visit to the People's Republic of China to consider matters relating to the certification of smallpox eradication, 14–30 July 1979.〈https://apps.who.int/iris/handle/10665/68275〉

Substances