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Review
. 2023 Apr 18;81(15):1505-1520.
doi: 10.1016/j.jacc.2023.02.023.

Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: JACC International

Amber Pirzada  1 , Jianwen Cai  2 , Gerardo Heiss  3 , Daniela Sotres-Alvarez  2 , Linda C Gallo  4 , Marston E Youngblood  2 , M Larissa Avilés-Santa  5 , Hector M González  6 , Carmen R Isasi  7 , Robert Kaplan  8 , John Kunz  9 , James P Lash  10 , David J Lee  11 , Maria M Llabre  12 , Frank J Penedo  12 , Carlos J Rodriguez  13 , Neil Schneiderman  12 , Tamar Sofer  14 , Gregory A Talavera  4 , Bharat Thyagarajan  15 , Sylvia Wassertheil-Smoller  7 , Martha L Daviglus  16
Affiliations
Review

Evolving Science on Cardiovascular Disease Among Hispanic/Latino Adults: JACC International

Amber Pirzada et al. J Am Coll Cardiol. .

Abstract

The landmark, multicenter HCHS/SOL (Hispanic Community Health Study/Study of Latinos) is the largest, most comprehensive, longitudinal community-based cohort study to date of diverse Hispanic/Latino persons in the United States. The HCHS/SOL aimed to address the dearth of comprehensive data on risk factors for cardiovascular disease (CVD) and other chronic diseases in this population and has expanded considerably in scope since its inception. This paper describes the aims/objectives and data collection of the HCHS/SOL and its ancillary studies to date and highlights the critical and sizable contributions made by the study to understanding the prevalence of and changes in CVD risk/protective factors and the burden of CVD and related chronic conditions among adults of diverse Hispanic/Latino backgrounds. The continued follow-up of this cohort will allow in-depth investigations on cardiovascular and pulmonary outcomes in this population, and data from the ongoing ancillary studies will facilitate generation of new hypotheses and study questions.

Keywords: Hispanic/Latino; cardiovascular disease; cohort study; study design.

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Conflict of interest statement

Funding Support and Author Disclosures The HCHS/SOL is a collaborative study supported by contracts from the National Heart, Lung, and Blood Institute to the University of North Carolina (HHSN268201300001I/N01-HC-65233), University of Miami (HHSN268201300004I/N01-HC-65234), Albert Einstein College of Medicine (HHSN268201300002I/N01-HC-65235), University of Illinois Chicago (HHSN268201300003I/N01-HC-65236, Northwestern University), and San Diego State University (HHSN268201300005I/N01-HC-65237). The following institutes/centers/offices have contributed to the HCHS/SOL through a transfer of funds to the National Heart, Lung, and Blood Institute: National Institute on Minority Health and Health Disparities, National Institute on Deafness and Other Communication Disorders, National Institute of Dental and Craniofacial Research, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Neurological Disorders and Stroke, National Institutes of Health Institution-Office of Dietary Supplements, and UC San Diego, National Institute on Aging: R01AG075758, R56 2-AG048642, RF1AG054548, RF1AG061022, RF1NS127266, R01AG061088, RF1AG077639. The funding agency had a role in the design and conduct of the HCHS/SOL; in the collection, analysis, and interpretation of HCHS/SOL data; and in the review and approval of this manuscript. The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Heart, Lung, and Blood Institute; the National Institutes of Health; or the U.S. Department of Health and Human Services. The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

Figure 1.
Figure 1.. HCHS/SOL Visits 1–3: Participant Recruitment and Retention
*The recruitment protocol included initial mailings to sampled addresses, telephone contacts for households with telephone numbers available, and in-person contacts. **Once contact was made, a brief household screener was administered to determine eligibility and implement the age sub-sampling procedure. ***Household members were screened for individual eligibility -- persons who could not speak ether English or Spanish, on active-duty military service, not currently living at home, planning to move from the area in the next six months, or physically unable to attend the clinic examination were ineligible.
Figure 2.
Figure 2.. HCHS/SOL Annual Follow-Up
* “N”: Expected interviews; “n”: Completed i nterviews
Figure 3.
Figure 3.
HCHS/SOL Visits 1–3 and Ancillary Studies: Timeline
Fig 4. Central Illustration.
Fig 4. Central Illustration.. HCHS/SOL Assessments and Measures: Evolving Science on Hispanic/Latino Health.
The HCHS/SOL and its ancillary studies have amassed comprehensive longitudinal data on adults of diverse Hispanic/Latino backgrounds and have made critical contributions to understanding risk factors for and burden of CVD and related chronic conditions in this population.
See this image and copyright information in PMC

Comment in

References

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