Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2023 Apr 6;24(7):6852.
doi: 10.3390/ijms24076852.

The Cellular Response to DNA Damage: From DNA Repair to Polyploidy and Beyond

Razmik Mirzayans  1
Affiliations
Editorial

The Cellular Response to DNA Damage: From DNA Repair to Polyploidy and Beyond

Razmik Mirzayans. Int J Mol Sci. .

Abstract

A major challenge in treating patients with solid tumors is posed by intratumor heterogeneity, with different sub-populations of cancer cells within the same tumor exhibiting therapy resistance through different biological processes [...].

PubMed Disclaimer

Conflict of interest statement

The author declares no conflict of interest.

Similar articles

See all similar articles

Cited by

References

    1. Editorial The ‘war on cancer’ isn’t yet won. Nature. 2022;601:297. doi: 10.1038/d41586-022-00109-3. - DOI - PubMed
    1. Liu J., Erenpreisa J., Sikora E. Polyploid giant cancer cells: An emerging new field of cancer biology. Semin. Cancer Biol. 2022;81:1–4. doi: 10.1016/j.semcancer.2021.10.006. - DOI - PubMed
    1. Bojko A., Staniak K., Czarnecka-Herok J., Sunderland P., Dudkowska M., Śliwińska M.A., Salmina K., Sikora E. Improved autophagic flux in escapers from doxorubicin-induced senescence/polyploidy of breast cancer cells. Int. J. Mol. Sci. 2020;21:6084. doi: 10.3390/ijms21176084. - DOI - PMC - PubMed
    1. Salmina K., Bojko A., Inashkina I., Staniak K., Dudkowska M., Podlesniy P., Rumnieks F., Vainshelbaum N.M., Pjanova D., Sikora E., et al. “Mitotic slippage” and extranuclear DNA in cancer chemoresistance: A focus on telomeres. Int. J. Mol. Sci. 2020;21:2779. doi: 10.3390/ijms21082779. - DOI - PMC - PubMed
    1. Anatskaya O.V., Vinogradov A.E., Vainshelbaum N.M., Giuliani A., Erenpreisa J. Phylostratic shift of whole-genome duplications in normal mammalian tissues towards unicellularity is driven by developmental bivalent genes and reveals a link to cancer. Int. J. Mol. Sci. 2020;21:8759. doi: 10.3390/ijms21228759. - DOI - PMC - PubMed

Publication types