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. 2023 Apr 6;13(7):1268.
doi: 10.3390/ani13071268.

The Spread of Peste Des Petits Ruminants Virus Lineage IV in West Africa

Emmanuel Couacy-Hymann  1 , Kouramoudou Berete  2 , Theophilus Odoom  3 , Lamouni Habibata Zerbo  4 , Koffi Yao Mathurin  1 , Valère Kouame Kouakou  1 , Mohamed Idriss Doumbouya  5 , Aminata Balde  2 , Patrick Tetteh Ababio  3 , Lalidia Bruno Ouoba  4 , Dominique Guigma  4 , Adama Dji-Tombo Drobo  4 , Mariétou Guitti  4 , Sherry Ama Mawuko Johnson  6 , David Livingstone Mawuko Blavo  6 , Giovanni Cattoli  7 , Charles E Lamien  7 , William G Dundon  7
Affiliations

The Spread of Peste Des Petits Ruminants Virus Lineage IV in West Africa

Emmanuel Couacy-Hymann et al. Animals (Basel). .

Abstract

Monitoring the transboundary spread of peste des petits ruminants (PPR) virus is an essential part of the global efforts towards the eradication of PPR by 2030. There is growing evidence that Lineage IV is becoming the predominant viral lineage, replacing Lineage I and II in West Africa. As part of a regional investigation, samples collected in Burkina Faso, Côte d'Ivoire, Guinea and Ghana were screened for the presence of PPRV. A segment of the nucleoprotein gene from positive samples was sequenced, and phylogenetic analysis revealed the co-circulation of Lineage II and IV in Burkina Faso, Côte d'Ivoire and Guinea, and the identification of Lineage IV in Ghana. These data will be of importance to local and regional authorities involved in the management of PPRV spread.

Keywords: Burkina Faso; Côte d’Ivoire; Ghana; Guinea; peste des petits ruminants; phylogenetic analysis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Map showing the sampling locations of PPR-positive samples. Lineage II and IV viruses are indicated by blue and red circles, respectively.
Figure 2
Figure 2
ML phylogenetic tree of the partial N gene sequences (219 nt) from the positive amplicons from this study combined with similar sequences available in GenBank. Sequences from Burkina Faso, Côte d’Ivoire, Ghana and Guinea are shown in blue, red, purple and green text, respectively. Lineages, subclades and bootstrap values > 70% are indicated. Note: For image clarity some of the sequences/subclades in Lineage IV have been collapsed. An un-collapsed tree is available as Supplementary Figure S1.
See this image and copyright information in PMC

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