Actionable Solutions to Achieve Health Equity in Chronic Liver Disease
- PMID: 37061105
- PMCID: PMC10330625
- DOI: 10.1016/j.cgh.2023.03.043
Actionable Solutions to Achieve Health Equity in Chronic Liver Disease
Abstract
There are well-described racial and ethnic disparities in the burden of chronic liver diseases. Hispanic persons are at highest risk for developing nonalcoholic fatty liver disease, the fastest growing cause of liver disease. Hepatitis B disproportionately affects persons of Asian or African descent. The highest rates of hepatitis C occur in American Indian and Alaskan Native populations. In addition to disparities in disease burden, there are also marked racial and ethnic disparities in access to treatments, including liver transplantation. Disparities also exist by gender and geography, especially in alcohol-related liver disease. To achieve health equity, we must address the root causes that drive these inequities. Understanding the role that social determinants of health play in the disparate health outcomes that are currently observed is critically important. We must forge and/or strengthen collaborations between patients, community members, other key stakeholders, health care providers, health care institutions, professional societies, and legislative bodies. Herein, we provide a high-level review of current disparities in chronic liver disease and describe actionable strategies that have potential to bridge gaps, improve quality, and promote equity in liver care.
Keywords: Chronic Liver Disease; Diversity; Health Disparities; Health Equity; Quality Improvement; Social Determinants.
Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.
Conflict of interest statement
Conflicts of interest
This author discloses the following: Jennifer C. Lai received personal fees from Novo Nordisk (Advisory Board) and Genfit (Consulting). The remaining authors disclose no conflicts.
Figures


Similar articles
-
Surveillance of health status in minority communities - Racial and Ethnic Approaches to Community Health Across the U.S. (REACH U.S.) Risk Factor Survey, United States, 2009.MMWR Surveill Summ. 2011 May 20;60(6):1-44. MMWR Surveill Summ. 2011. PMID: 21597458
-
Mortality Disparities in Racial/Ethnic Minority Groups in the Veterans Health Administration: An Evidence Review and Map.Am J Public Health. 2018 Mar;108(3):e1-e11. doi: 10.2105/AJPH.2017.304246. Am J Public Health. 2018. PMID: 29412713 Free PMC article. Review.
-
Racial-ethnic disparities in stroke care: the American experience: a statement for healthcare professionals from the American Heart Association/American Stroke Association.Stroke. 2011 Jul;42(7):2091-116. doi: 10.1161/STR.0b013e3182213e24. Epub 2011 May 26. Stroke. 2011. PMID: 21617147
-
State of the Nation's Cardiovascular Health and Targeting Health Equity in the United States: A Narrative Review.JAMA Cardiol. 2021 Aug 1;6(8):963-970. doi: 10.1001/jamacardio.2021.1137. JAMA Cardiol. 2021. PMID: 34009231 Free PMC article. Review.
-
Exploring the complexity and spectrum of racial/ethnic disparities in colon cancer management.Int J Equity Health. 2023 Apr 14;22(1):68. doi: 10.1186/s12939-023-01883-w. Int J Equity Health. 2023. PMID: 37060065 Free PMC article.
Cited by
-
The Multi-dimensional Challenge of Poor Oral Health in Cirrhosis-Disparities and Solutions.Gastroenterology. 2024 May;166(5):717-722. doi: 10.1053/j.gastro.2024.01.010. Epub 2024 Jan 13. Gastroenterology. 2024. PMID: 38224859 Free PMC article. No abstract available.
-
Undiagnosed Cirrhosis and Hepatic Encephalopathy in a National Cohort of Veterans With Dementia.JAMA Netw Open. 2024 Jan 2;7(1):e2353965. doi: 10.1001/jamanetworkopen.2023.53965. JAMA Netw Open. 2024. PMID: 38294815 Free PMC article.
-
Unveiling Disparities in Heart Failure and Cirrhosis Related Mortality: CDC WONDER 1999 to 2020.Dig Dis Sci. 2025 Jun;70(6):2128-2137. doi: 10.1007/s10620-025-08970-8. Epub 2025 Apr 10. Dig Dis Sci. 2025. PMID: 40208496 Free PMC article.
-
The Microbiome and Metabolic Dysfunction-Associated Steatotic Liver Disease.Int J Mol Sci. 2025 Mar 22;26(7):2882. doi: 10.3390/ijms26072882. Int J Mol Sci. 2025. PMID: 40243472 Free PMC article. Review.
-
Managing Nonalcoholic Fatty Liver Disease Through Structured Lifestyle Modification Interventions.Am J Lifestyle Med. 2025 May 26:15598276251346717. doi: 10.1177/15598276251346717. Online ahead of print. Am J Lifestyle Med. 2025. PMID: 40438150 Free PMC article. Review.
References
-
- https://www.nimhd.nih.gov/about/strategic-plan/nih-strategic-plan-defini.... Accessed February 7, 2023.
-
- Braveman PA, Arkin E, Orleans T, et al. What is health equity? And what difference does a definition make? Princeton, NJ: Robert Wood Johnson Foundation, 2017.
-
- https://www.nimhd.nih.gov/about/overview/research-framework/nimhd-framew.... Accessed February 7, 2023.
Publication types
MeSH terms
Grants and funding
- R21 TR003095/TR/NCATS NIH HHS/United States
- P30 DK026743/DK/NIDDK NIH HHS/United States
- I01 CX001076/CX/CSRD VA/United States
- U01 DK130185/DK/NIDDK NIH HHS/United States
- K08 CA255413/CA/NCI NIH HHS/United States
- R01 HS025412/HS/AHRQ HHS/United States
- R01 CA256977/CA/NCI NIH HHS/United States
- L60 MD012017/MD/NIMHD NIH HHS/United States
- U01 CA230997/CA/NCI NIH HHS/United States
- R01 AA029398/AA/NIAAA NIH HHS/United States
- R01 MD012565/MD/NIMHD NIH HHS/United States
- R01 MD017063/MD/NIMHD NIH HHS/United States
- P30 CA240139/CA/NCI NIH HHS/United States
- R01 AG059183/AG/NIA NIH HHS/United States
LinkOut - more resources
Full Text Sources
Medical