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. 2022 Oct;29(4):201-202.
doi: 10.1177/09727531221125589. Epub 2022 Sep 15.

Switching to Tenecteplase from Alteplase for Ischemic Stroke: Is it the Time for Universal Adoption?

Sanjeev Kharel  1 , Riwaj Bhagat  2
Affiliations

Switching to Tenecteplase from Alteplase for Ischemic Stroke: Is it the Time for Universal Adoption?

Sanjeev Kharel et al. Ann Neurosci. 2022 Oct.
No abstract available

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Conflict of interest statement

The authors declared no potential conflicts of interest with respect to the research, authorship and/or publication of this article.

References

    1. Coutts SB, Yu AYX.. Tenecteplase for acute stroke: the thrombolysis puzzle. The Lancet Neurology 2022; 21(6): 496–497. - PubMed
    1. Katsanos AH, Psychogios K, Turc G, Sacco S, de Sousa DA, de Marchis GM, et al. Off-label use of tenecteplase for the treatment of acute ischemic stroke. JAMA Network Open 2022; 5(3): e224506. - PMC - PubMed
    1. Burgos AM, Saver JL.. Evidence that tenecteplase is noninferior to alteplase for acute ischemic stroke. Stroke 2019; 50(8): 2156–2162. - PubMed
    1. Menon BK, Buck BH, Singh N, Deschaintre Y, Almekhlafi MA, Coutts SB, et al. Intravenous tenecteplase compared with alteplase for acute ischemic stroke in Canada (AcT): A pragmatic, multicentre, open-label, registry-linked, randomised, controlled, non-inferiority trial. The Lancet 2022; 400(10347):161–169. - PubMed
    1. Katsanos AH, Safouris A, Sarraj A, Magoufis G, Leker RR, Khatri P, et al. Intravenous thrombolysis with tenecteplase in patients with large vessel occlusions. Stroke 2021; 52(1): 308–312. - PubMed