Osteosarcoma of the mandible: A case with a clinical appearance similar to benign lesions

Abstract

A 34-year-old woman with complaints of mandibular swelling that started 4 months earlier was referred to the Oral Diseases Department. Based on the clinical and radiographic appearance, the primary diagnosis was an intraosseous reactive lesion. However, the result of histopathology indicated osteosarcoma.

Keywords: benign lesions; diagnosis; mandible; osteosarcoma.

FIGURE 1

Clinical appearance: a dome‐shaped exophytic lesion with intact mucosa in the buccal vestibule of the right mandible.

FIGURE 2

Panoramic appearance: poorly defined radiolucent lesion in the lower right third and fifth teeth, fine bone structure inside the lesion and band‐like PDL widening in the distal lower right second tooth and the mesial lower right third tooth are visible. In addition, the displacement of the lower right third to fifth teeth, their root erosion and the destruction of the upper border of the lower right alveolar canal can be viewed.

FIGURE 3

CBCT appearance: a radiolucent lesion with distinct borders, multilocular wispy (cut no. 10) along with perforation of the buccal and lingual cortex, root resorption and tooth displacement are visible.

FIGURE 4

Histopathological appearance (H&E staining): an image with 20× magnification showing malignant hyperchromatic cells and chondroid areas (A). An image with 40× magnification showing the osteoid areas within the malignant cells (B).