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Review
. 2022 Dec 22;50(2):123-128.
doi: 10.1159/000528077. eCollection 2023 Apr.

Strengthening Blood Regulatory Systems to Tackle Africa's Unmet Needs for Blood and Blood Products

Washington T Samukange  1   2 , Chancelar Kafere  1 , Kristina Heinrich  1 , George T Sabblah  3 , Mwewa M Siame  4 , Libert Chirinda  5 , Jens Reinhardt  6 , Anneliese Hilger  6
Affiliations
Review

Strengthening Blood Regulatory Systems to Tackle Africa's Unmet Needs for Blood and Blood Products

Washington T Samukange et al. Transfus Med Hemother. .

Abstract

Background: Assuring the quality and safety of blood and blood components is an essential element of health care in all countries and requires government commitment and legal frameworks. Ineffective regulation of blood and blood components has far-reaching consequences that are not limited to the affected countries but also have extensive global implications.

Summary: In this review, we summarize the work of the project BloodTrain funded by the German Ministry of Health within the framework of the Global Health Protection Programme to strengthen regulatory structures in Africa that are imperative to guarantee the improved availability, safety, and quality of blood and blood products.

Key messages: Intense interaction with the stakeholders in African partner countries lead to first measurable successes in the strengthening of blood regulation, as shown here for hemovigilance.

Keywords: Africa; Blood safety; Hemovigilance; Regulation of blood and blood products.

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

Fig. 1.
Fig. 1.
BloodTrain strategic approach (adopted from the WHO RSS 5-step capacity-building programme and the Promoting Quality Medicines Program, implemented by the US Pharmacopeial Convention (USP).
Fig. 2.
Fig. 2.
Implementation of BloodTrain strategic plan.
See this image and copyright information in PMC

References

    1. Burnouf T. Blood products unmet needs for essential medicines. Lancet Haematol. 2019;6:e598–e599. - PubMed
    1. Roberts N, James S, Delaney M, Fitzmaurice C. The global need and availability of blood products a modelling study. Lancet Haematol. 2019;6:e606–15. - PubMed
    1. Epstein JS. Best practices in regulation of blood and blood products. Biologicals. 2012;40:200–204. - PubMed
    1. Khadem Broojerdi A, Baran Sillo H, Ostad Ali Dehaghi R, Ward M, Refaat M, Parry J. The World health organization global benchmarking tool an instrument to strengthen medical products regulation and promote universal health coverage. Front Med. 2020;7:457. - PMC - PubMed
    1. Guzman J, O'Connell E, Kikule K, Hafner T. The WHO Global Benchmarking Tool a game changer for strengthening national regulatory capacity. BMJ Glob Health. 2020;5 - PMC - PubMed