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Editorial
. 2023 Oct;29(5):493-497.
doi: 10.1177/15910199231170283. Epub 2023 Apr 17.

Endovascular thrombectomy of large ischemic strokes: Reimagining the boundaries of reperfusion

Ahmad A Ballout  1
Affiliations
Editorial

Endovascular thrombectomy of large ischemic strokes: Reimagining the boundaries of reperfusion

Ahmad A Ballout. Interv Neuroradiol. 2023 Oct.

Abstract

The cumulative results of the SELECT-2, ANGEL-ASPECTS, and RESCUE-JAPAN LIMIT clinical trials suggest that endovascular thrombectomy performed within 24 h of symptom onset, in patients presenting with large ischemic strokes, defined by parenchymal and/or perfusion imaging, is safe and is associated with better functional outcomes with a treatment effect that persisted across all subgroups of patients. Our aim was to review these studies and to discuss the implications that these studies may have on patient selection, systems of care, and the utility of our imaging modalities.

Keywords: Mechanical thrombectomy; large core; large ischemic stroke.

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Conflict of interest statement

Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Rates of good outcome (MRS 0–3) across all three trials. Infarction growth rates (ml/h) calculated based on the median infarction volume divided by median time to randomization.
See this image and copyright information in PMC

References

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