Approach to schizophrenia
- PMID: 37070777
- DOI: 10.1111/imj.16068
Approach to schizophrenia
Abstract
Schizophrenia is the most common of a group of psychotic disorders that occur in approximately 3% of the population over the lifespan. It has clear genetic antecedents, which are shared across the spectrum of psychotic disorders; however, a range of other biological and social factors influence the onset and treatment of the disorder. Schizophrenia is diagnosed by a characteristic set of symptoms (positive, negative, disorganisation, cognitive and affective) accompanied by a functional decline. Investigations are used to exclude other organic causes of psychosis and to provide a baseline for the negative effects of pharmacological treatments. Treatment requires a combination of pharmacological and psychosocial interventions. Physical health is poor in this group of people and this is not helped by inconsistent care from health services. Although earlier intervention has improved the immediate outcomes, the longer-term outcome has not significantly shifted.
Keywords: physical health; psychosis; schizophrenia; treatment.
© 2023 The Author. Internal Medicine Journal published by John Wiley & Sons Australia, Ltd on behalf of Royal Australasian College of Physicians.
Comment in
-
A closer look at late-onset psychoses for the general internist.Intern Med J. 2023 Aug;53(8):1512. doi: 10.1111/imj.16196. Intern Med J. 2023. PMID: 37599230 No abstract available.
References
-
- Saha S, Chant D, Welham J, McGrath J. A systematic review of the prevalence of schizophrenia. PLoS Med 2005; 2: e141.
-
- Solmi M, Radua J, Olivola M, Croce E, Soardo L, Salazar de Pablo G et al. Age at onset of mental disorders worldwide: large-scale meta-analysis of 192 epidemiological studies. Mol Psychiatry 2022; 27: 281-95.
-
- He H, Liu Q, Li N, Guo L, Gao F, Bai L et al. Trends in the incidence and DALYs of schizophrenia at the global, regional and national levels: results from the Global Burden of Disease Study 2017. Epidemiol Psychiatr Sci 2020; 29: e91.
-
- McGrath J, Saha S, Welham J, El Saadi O, MacCauley C, Chant D. A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med 2004; 2: 13.
-
- Guloksuz S, van Os J. The slow death of the concept of schizophrenia and the painful birth of the psychosis spectrum. Psychol Med 2018; 48: 229-44.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical