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. 2023 Jun 15;31(12):614-619.
doi: 10.5435/JAAOS-D-22-01179. Epub 2023 Apr 14.

Periarticular Injection in Total Knee Arthroplasty

Andrew Schwartz  1 , Niall H Cochrane, William A Jiranek, Sean P Ryan
Affiliations

Periarticular Injection in Total Knee Arthroplasty

Andrew Schwartz et al. J Am Acad Orthop Surg. .

Abstract

Optimal pain management after total knee arthroplasty (TKA) can expedite postoperative recovery, improve perioperative outcomes, and increase patient satisfaction. Periarticular injections (PAIs) have become increasingly used to improve pain management after TKA. Similar to peripheral nerve blocks, the use of intraoperative PAIs can lower pain scores and expedite discharge from the hospital. However, there is notable variability in the ingredients and administration techniques of PAIs. Currently, no standard of care exists for PAIs, especially in the setting of adjuvant peripheral nerve blocks. This study seeks to evaluate the ingredients, administration techniques, and outcomes of PAIs used during TKA.

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Conflict of interest statement

Conflicts of interest and source of funding: Disclosures related to conflict of interest of each author can be found on the disclosure website at www.aaos.org .

References

    1. Chung AS, Spangehl MJ: Peripheral nerve blocks vs periarticular injections in total knee arthroplasty. J Arthroplasty 2018;33:3383-3388.
    1. Ross JA, Greenwood AC, Sasser P III, Jiranek WA: Periarticular injections in knee and hip arthroplasty: Where and what to inject. J Arthroplasty 2017;32:S77-S80.
    1. Busch CA, Shore BJ, Bhandari R, et al.: Efficacy of periarticular multimodal drug injection in total knee arthroplasty. A randomized trial. J Bone Joint Surg 2006;88:959-963.
    1. Hirasawa Y, Okajima S, Ohta M, Tokioka T: Nerve distribution to the human knee joint: Anatomical and immunohistochemical study. Int Orthop 2000;24:1-4.
    1. Biedert RM, Stauffer E, Friederich NF: Occurrence of free nerve endings in the soft tissue of the knee joint: A histologic investigation. Am J Sports Med 1992;20:430-433.

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