2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Wei-Che Lin^{1

2

3}, Wen-Chieh Chen⁴, Pei-Wen Wang⁴, Yi-Chia Chan⁵, Yen-Hsiang Chang⁶, Harn-Shen Chen^{7

8}, Szu-Tah Chen⁹, Wei-Chih Chen¹⁰, Kai-Lun Cheng¹¹, Shun-Yu Chi⁵, Pi-Ling Chiang¹, Chen-Kai Chou⁴, Feng-Fu Chou⁵, Shun-Chen Huang¹², Feng-Hsuan Liu⁹, Sheng-Dean Luo¹⁰, Fen-Yu Tseng^{13

14}, Chih-Yuan Wang¹⁵, Wen-Hung Wang¹⁶, Ming-Hsun Wu¹⁷

Affiliations

¹ Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
² Department of Radiology, Jen Ai Chang Gung Health, Taichung, Taiwan.
³ School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
⁴ Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
⁵ Division of General Surgery and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
⁶ Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
⁷ Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
⁸ Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
⁹ Division of Endocrinology and Metabolism, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
¹⁰ Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
¹¹ Department of Medical Imaging, Chung Shan Medical University Hospital, School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan.
¹² Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
¹³ Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
¹⁴ Division of Endocrinology and Metabolism, Department of Internal Medicine, Taitung Christian Hospital, Taitung, Taiwan.
¹⁵ Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
¹⁶ Department of Otolaryngology, Cathay General Hospital, Taipei City; Department of Otolaryngology, Sijhih Cathay General Hospital, New Taipei City; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
¹⁷ Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

PMID: 37072152
PMCID: PMC10331054
DOI: 10.14366/usg.22126

2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Wei-Che Lin et al. Ultrasonography. 2023 Jul.

. 2023 Jul;42(3):357-375.

doi: 10.14366/usg.22126. Epub 2022 Nov 19.

Authors

Affiliations

¹ Department of Diagnostic Radiology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
² Department of Radiology, Jen Ai Chang Gung Health, Taichung, Taiwan.
³ School of Medicine, College of Medicine, National Sun Yat-sen University, Kaohsiung, Taiwan.
⁴ Division of Endocrinology and Metabolism, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
⁵ Division of General Surgery and Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
⁶ Department of Nuclear Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
⁷ Faculty of Medicine, School of Medicine, National Yang-Ming University, Taipei, Taiwan.
⁸ Section of Endocrinology and Metabolism, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
⁹ Division of Endocrinology and Metabolism, Department of Internal Medicine, Linkou Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan.
¹⁰ Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
¹¹ Department of Medical Imaging, Chung Shan Medical University Hospital, School of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung, Taiwan.
¹² Department of Pathology, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan.
¹³ Division of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.
¹⁴ Division of Endocrinology and Metabolism, Department of Internal Medicine, Taitung Christian Hospital, Taitung, Taiwan.
¹⁵ Department of Internal Medicine, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei, Taiwan.
¹⁶ Department of Otolaryngology, Cathay General Hospital, Taipei City; Department of Otolaryngology, Sijhih Cathay General Hospital, New Taipei City; School of Medicine, Fu-Jen Catholic University, New Taipei City, Taiwan.
¹⁷ Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.

PMID: 37072152
PMCID: PMC10331054
DOI: 10.14366/usg.22126

Abstract

Radiofrequency ablation (RFA) is a minimally invasive management strategy that has been widely applied for benign and recurrent malignant thyroid lesions as an alternative to surgery in Taiwan. Members of academic societies for specialists in interventional radiology, endocrinology, and endocrine surgery collaborated to develop the first consensus regarding thyroid RFA in Taiwan. The modified Delphi method was used to reach a consensus. Based on a comprehensive review of recent and valuable literature and expert opinions, the recommendations included indications, pre-procedural evaluations, procedural techniques, post-procedural monitoring, efficacy, and safety, providing a comprehensive review of the application of RFA. The consensus effectively consolidates advice regarding thyroid RFA in clinical practice for local experts.

Keywords: Consensus; Locally recurrent thyroid cancer; Nodule; Radiofrequency ablation; Thyroid; Ultrasound.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

**Fig. 1.. Protocol for reaching the consensus.**

See this image and copyright information in PMC

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References

1. Park HS, Baek JH, Na DG. Benign thyroid nodules treatment using percutaneous laser ablation (PLA) and radiofrequency ablation (RFA) Int J Hyperthermia. 2017;33:953–954. - PubMed
1. Jeong WK, Baek JH, Rhim H, Kim YS, Kwak MS, Jeong HJ, et al. Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients. Eur Radiol. 2008;18:1244–1250. - PubMed
1. Spiezia S, Garberoglio R, Milone F, Ramundo V, Caiazzo C, Assanti AP, et al. Thyroid nodules and related symptoms are stably controlled two years after radiofrequency thermal ablation. Thyroid. 2009;19:219–225. - PubMed
1. Jung SL, Baek JH, Lee JH, Shong YK, Sung JY, Kim KS, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol. 2018;19:167–174. - PMC - PubMed
1. Ha EJ, Baek JH, Che Y, Chou YH, Fukunari N, Kim JH, et al. Radiofrequency ablation of benign thyroid nodules: recommendations from the Asian Conference on Tumor Ablation Task Force. Ultrasonography. 2021;40:75–82. - PMC - PubMed

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2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Affiliations

2022 Taiwan clinical multicenter expert consensus and recommendations for thyroid radiofrequency ablation

Authors

Affiliations

Abstract

Conflict of interest statement

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Abstract

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