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Review
. 2023 Apr-Jun;106(2):368504231168821.
doi: 10.1177/00368504231168821.

Normal saline: Past, present, and future

Xinwen Liu  1 , Mengkai Lu  1
Affiliations
Review

Normal saline: Past, present, and future

Xinwen Liu et al. Sci Prog. 2023 Apr-Jun.

Abstract

Normal saline (NS) is the most widely used agent in the medical field. However, from its origin to its widespread application, it remains a mystery. Moreover, there is an ongoing debate on whether its existence is reasonable, harmful to the human body, or will still exist in the future. The current review traces back to the origins of NS and provides a brief overview of the current situation of infusion. The purpose may shed some light on the possibility of the existence of NS in the future by elaborating on the origin of NS and the research status of the impact of NS on the human body.

Keywords: 0.9% sodium chloride solution; Normal saline; balanced crystalloid solutions; history; lactated Ringer's solution.

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Conflict of interest statement

The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

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