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Case Reports
. 1986 Apr;29(4):560-4.
doi: 10.1002/art.1780290416.

D-penicillamine-induced polymyositis in patients with rheumatoid arthritis

K Takahashi, T Ogita, H Okudaira, S Yoshinoya, H Yoshizawa, T Miyamoto
Case Reports

D-penicillamine-induced polymyositis in patients with rheumatoid arthritis

K Takahashi et al. Arthritis Rheum. 1986 Apr.

Abstract

Among 329 patients with rheumatoid arthritis treated with D-penicillamine (DP), we found 4 cases of polymyositis. This incidence was significantly higher than the expected coincidence of rheumatoid arthritis and polymyositis/dermatomyositis or than the presumed frequency of this complication among patients treated with DP. In the present report, we summarize and discuss the clinical findings in DP-induced polymyositis/dermatomyositis in our patients and others described in the literature.

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