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. 2023 Jul;182(7):3093-3099.
doi: 10.1007/s00431-023-04951-z. Epub 2023 Apr 19.

Retinopathy of prematurity detection: a retrospective quality improvement project before-after implementation of retinal digital imaging for screening

Marie-Gwenola Desurmont  1 , Dominique Bremond-Gignac  1   2 , Héloïse Torchin  3   4 , Brigitte Vacherot  3 , Pierre-Henri Jarreau  3   4 , Alejandra Daruich  5   6
Affiliations

Retinopathy of prematurity detection: a retrospective quality improvement project before-after implementation of retinal digital imaging for screening

Marie-Gwenola Desurmont et al. Eur J Pediatr. 2023 Jul.

Abstract

Screening of retinopathy of prematurity (ROP) was modified in a level-3 neonatal intensive care unit by the introduction of a wide-field retinal imaging. The aim of this study was to evaluate whether retinopathy of prematurity (ROP) diagnosis was improved or not compared to previously used binocular indirect ophthalmoscopy (BIO). This was a retrospective, uncontrolled, quality improvement project. Records of consecutive premature newborns screened for ROP over two 1-year periods were reviewed. Systemic factors potentially influencing the occurrence of ROP were investigated using uni- and multivariable linear regression followed by stepwise forward regression. ROP screening was performed by ophthalmologists using BIO in 2014, and digital wide-field retinal imaging (Panocam™ pro) in 2019. Records of N = 297 patients were analyzed (N = 159 in 2014 and N = 138 in 2019). The proportion of ROP diagnosed at any stage, over the total number of neonates screened, was significantly higher in 2019 (n = 46/138, 33.1%) compared to 2014 (n = 11/159, 6.9%) (p < 0.0001). Most neonates presented with mild forms of ROP during both 1-year periods analyzed. After adjustment for all parameters influencing ROP occurrence, the variables contributing independently to the diagnosis of any stage of ROP were birth weight (p = 0.002), duration of mechanical ventilation (p = 0.028) and wide-field fundus camera-assisted screening (p < 0.001).

Conclusion: After adjusting for many recognized systemic factors influencing the development of ROP, screening by wide-field digital retinal imaging was independently associated with higher ROP detection.

What is known: • No consensus has been reached to replace binocular indirect ophthalmoscopy by retinal imaging for ROP screening. • Diagnostic accuracy and high sensitivity and specificity has been reported for wide-field digital imaging.

What is new: • The introduction of wide-field imaging for ROP screening in at level-3 reference center was independently associated to higher ROP detection.

Keywords: ROP; Screening; Wide-field digital retinal imaging.

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References

    1. Ludwig CA, Chen TA, Hernandez-Boussard T et al (2017) The epidemiology of retinopathy of prematurity in the United States. Ophthalmic Surg Lasers Imaging Retina 48:553–562. https://doi.org/10.3928/23258160-20170630-06 - DOI - PubMed
    1. Painter SL, Wilkinson AR, Desai P et al (2015) Incidence and treatment of retinopathy of prematurity in England between 1990 and 2011: database study. Br J Ophthalmol 99:807–811. https://doi.org/10.1136/bjophthalmol-2014-305561 - DOI - PubMed
    1. Beby F, Burillon C, Putet G, Denis Ph (2004) Rétinopathie du prématuré : résultats de l’examen du fond d’œil chez 94 enfants à risque. J Fr Ophtalmol 27:337–344. https://doi.org/10.1016/S0181-5512(04)96138-4 - DOI - PubMed
    1. Austeng D (2009) Incidence of retinopathy of prematurity in infants born before 27 weeks’ gestation in Sweden. Arch Ophthalmol 127:1315. https://doi.org/10.1001/archophthalmol.2009.244 - DOI - PubMed
    1. Slidsborg C, Forman JL, Rasmussen S et al (2011) A new risk-based screening criterion for treatment-demanding retinopathy of prematurity in Denmark. Pediatrics 127:e598–e606. https://doi.org/10.1542/peds.2010-1974 - DOI - PubMed

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