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Case Reports
. 2023 Apr 10:2023:6036567.
doi: 10.1155/2023/6036567. eCollection 2023.

Histopathological Characterization of a Series of Oral Basaloid Squamous Cell Carcinoma

Neetu Jain  1 , Toniya Raut  1 , Shashi Keshwar  1 , Ashish Shrestha  1 , Mehul Rajesh Jaisani  2 , Deepak Paudel  3
Affiliations
Case Reports

Histopathological Characterization of a Series of Oral Basaloid Squamous Cell Carcinoma

Neetu Jain et al. Case Rep Dent. .

Abstract

Basaloid squamous cell carcinoma (BSCC) is a rare, distinctive, and aggressive variant of squamous cell carcinoma (SCC) primarily seen in the upper aerodigestive tract with epiglottis, soft palate, and base of the tongue being site of high preference in head and neck region. It differs from conventional SCC histologically and immunologically, is most frequently found in males in their sixth and seventh decades, and is frequently linked to alcohol and tobacco use. High stage disease with distant metastases, a high recurrence rate, and a dismal prognosis is how BSCC typically manifests. In the present article, we report four cases of BSCC.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
10× view. A: squamous cells; B: basaloid cells; C: keratin pearl; and D: area of comedo necrosis.
Figure 2
Figure 2
40× view. A: mitotic figure.
Figure 3
Figure 3
10× view. A: basaloid cells; B: mitotic figure; and C: inflammatory cells.
Figure 4
Figure 4
40× view. A: basaloid cells; and B: mitotic figure.
Figure 5
Figure 5
4× view. A: basaloid cells; B: keratin pearl; and C: comedo necrosis.
Figure 6
Figure 6
10× view. A: squamous cells; B: basaloid cells with peripheral palisading; and C: comedo necrosis.
Figure 7
Figure 7
4× view: islands of basaloid cells intermixed with squamous cells.
Figure 8
Figure 8
10× view. A: basaloid cells with peripheral palisading.
See this image and copyright information in PMC

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