On the prediction of premature births in Hispanic labour patients using uterine contractions, heart beat signals and prediction machines

Abstract

Preterm birth is a global epidemic affecting millions of mothers across different ethnicities. The cause of the condition remains unknown but has recognised health-based implications, in addition to financial and economic ones. Machine Learning methods have enabled researchers to combine datasets using uterine contraction signals with various forms of prediction machines to improve awareness of the likelihood of premature births. This work investigates the feasibility of enhancing these prediction methods using physiological signals including uterine contractions, and foetal and maternal heart rate signals, for a population of south American women in active labour. As part of this work, the use of the Linear Series Decomposition Learner (LSDL) was seen to lead to an improvement in the prediction accuracies of all models, which included supervised and unsupervised learning models. The results from the supervised learning models showed high prediction metrics upon the physiological signals being pre-processed by the LSDL for all variations of the physiological signals. The unsupervised learning models showed good metrics for the partitioning of Preterm/Term labour patients from their uterine contraction signals but produced a comparatively lower set of results for the various kinds of heart rate signals investigated.

Keywords: biocybernetics; decision support systems; learning (artificial intelligence); medical control systems; medical signal processing; physiological models; signal classification; support vector machines.

FIGURE 1

Images showing various acquisition settings and protocols from related literature [17, 18].

FIGURE 2

Annotated image of the human heart [27].

FIGURE 3

An illustration of simultaneous monitoring of both foetus heartbeat and uterine contraction [29].

FIGURE 4

PCA visualisation plot of the various data classes.