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. 2023 Aug 11;110(9):1112-1115.
doi: 10.1093/bjs/znad099.

Outcomes of livers from donation after circulatory death donors with extended agonal phase and the adjunct of normothermic regional perfusion

James A Richards  1   2   3   4   5 , Rohit Gaurav  1   4 , Sara S Upponi  1   4   6 , Lisa Swift  1 , Corrina Fear  1 , Gwilym J Webb  1   7 , Michael E D Allison  1   4   7 , Christopher J E Watson  1   2   3   4 , Andrew J Butler  1   2   3   4
Affiliations

Outcomes of livers from donation after circulatory death donors with extended agonal phase and the adjunct of normothermic regional perfusion

James A Richards et al. Br J Surg. .

Abstract

The liver performs important functions that are essential for life. If the liver fails, patients will die unless they receive a new liver from a donor (transplant). Unfortunately, there are not enough livers for everyone and some patients die while waiting for a suitable organ. This article describes a novel technique that allows resuscitation and testing of a potential donor liver so that more patients can safely receive a transplant.

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Figures

Fig. 1
Fig. 1
Outcomes compared by agonal time a–c Kaplan–Meier plots showing a patient, b graft, and c transplant survival; aP = 0.929, bP = 0.256, cP = 0.929 (Mantel–Cox analysis). d Box-and-whisker graph showing Model for Early Allograft Function (MEAF) scores. Median (bold line), i.q.r. (box), and range (whiskers) are shown; *P = 0.871 (Mann–Whitney U test).
Fig. 2
Fig. 2
In situ normothermic regional perfusion decision-making algorithm NRP, in situ normothermic regional perfusion.
See this image and copyright information in PMC

References

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