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Case Reports
. 2023 May:106:108213.
doi: 10.1016/j.ijscr.2023.108213. Epub 2023 Apr 16.

Recurrent primary cutaneous granular cell tumor of the neck in an Asian women: A case report

Ciniraj Raveendran  1 , Ruby Elias  2 , Sabu Parameswaran  3 , I P Yadev  4
Affiliations
Case Reports

Recurrent primary cutaneous granular cell tumor of the neck in an Asian women: A case report

Ciniraj Raveendran et al. Int J Surg Case Rep. 2023 May.

Abstract

Introduction and importance: Granular cell tumors are uncommon neoplasms. They appear in the skin, subcutaneous tissues, and many internal organs. It is essential to diagnose this disease because it mimics other tumors clinically. We report this case because of the rarity of tumors in Asians and the necessity of excision with clear margins.

Case presentation: A 55-year-old Indian woman reported swelling in the right side of the neck for six months and gradually increasing in size. Two years ago, she had a similar swelling excised from her neck. She had wide local excision of the tumor with wider margins in the plastic surgery department, and histopathology revealed a granular cell tumor with clear margins. She is undergoing close follow-up with history and physical examination with no evidence of disease recurrence.

Clinical discussion: Granular cell tumors can have recurrences. These slow-growing tumors appear benign. Histopathological examination with careful assessment of high-risk features is vital in evaluating Granular cell tumors. Wide local excision with clear margins is the mainstay of treatment.

Conclusion: Achieving clear margins in the head and neck area is sometimes tricky for granular cell tumors. Margin positivity is associated with a high risk of local recurrence and needs re-excision of the tumor for adequate local control.

Keywords: Case report; Excision; Granular cell tumor; Neck; Recurrence.

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Conflict of interest statement

Conflict of interest statement All authors declare no conflict of interest.

Figures

Fig. 1
Fig. 1
Photograph of the patient showing nodular swelling 3 × 3 cm on the right side of the neck.
Fig. 2
Fig. 2
Macroscopy: Skin with an ill circumscribed grey white firm lesion (2.4 × 1.3 × 0.5 cm) in the dermis extending to the subcutaneous fat.
Fig. 3
Fig. 3
Pseudoepitheliomatous hyperplasia of the overlying skin Hematoxylin and Eosin, magnification 10×.
Fig. 4
Fig. 4
Skin with dermis and subcutis showing sheets of large cells Hematoxylin and Eosin, magnification 4×.
Fig. 5
Fig. 5
Large polygonal cells with abundant eosinophilic granular cytoplasm and round uniform nucleus Hematoxylin and Eosin, magnification 40×.
Fig. 6
Fig. 6
Timeline of events, interventions, and outcome (GCT- Granular Cell Tumor).
See this image and copyright information in PMC

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