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Case Reports
. 2023 Jul-Aug;98(4):539-541.
doi: 10.1016/j.abd.2022.01.014. Epub 2023 Apr 20.

Dermoscopy of circumscribed palmar hypokeratosis

Érika Hiromi Hayacibara  1 , Sheila Zanconato Sales  2 , Rute Facchini Lellis  3 , Rosana Lazzarini  4
Affiliations
Case Reports

Dermoscopy of circumscribed palmar hypokeratosis

Érika Hiromi Hayacibara et al. An Bras Dermatol. 2023 Jul-Aug.
No abstract available

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Figures

Figure 1
Figure 1
(A) Clinical record of the lesion after four years of evolution. (B) Detail of the lesion at higher magnification: dermatosis on the thenar region of the left palm, characterized by a slightly erythematous area with raised borders.
Figure 2
Figure 2
Dermoscopic image, with polarized light, showing white dots (blue arrow), red dots (red arrow) and whitish striae in the central region of the lesion.
Figure 3
Figure 3
In greater detail, dermoscopic image showing a clear difference in relief between the border and the center of the lesion.
Figure 4
Figure 4
Dermoscopic image of the medial border of the lesion. At this higher magnification, it is possible to see the “step-ladder” pattern corresponding to the anatomopathological image in Fig. 5.
Figure 5
Figure 5
Histopathology of the lesion, showing a well-circumscribed area of clear cut decrease in the stratum corneum (arrow), (Hematoxylin & eosin, x40).
See this image and copyright information in PMC

References

    1. Pérez A., Rütten A., Gold R., Urbina F., Misad C., Izquierdo M.J., et al. Circumscribed palmar or plantar hypokeratosis: a distinctive epidermal malformation of the palms or soles. J Am Acad Dermatol. 2002;47:21–27. - PubMed
    1. Rocha LK, Nico MM. Circumscribed palmoplantar hypokeratosis: report of two Brazilian cases. An Bras Dermatol. 2013;88:623–626. - PMC - PubMed
    1. Ishiko A., Dekio I., Fujimoto A., Kameyama K., Sakamoto M., Benno Y., et al. Abnormal keratin expression in circumscribed palmar hypokeratosis. J Am Acad Dermatol. 2007;57:285–291. - PubMed
    1. Nishimura M., Nishie W., Nakazato S., Nemoto-Hasebe I., Fujita Y., Shimizu H. Circumscribed palmar hypokeratosis: correlation between histopathological patterns and dermoscopic findings. Br J Dermatol. 2012;167:221–222. - PubMed
    1. Tanioka M., Miyagawa-Hayashino A., Manabe T., Toichi E., Miyachi Y., Takahashi K. Circumscribed palmo-plantar hypokeratosis: a disease with two subtypes. J Invest Dermatol. 2009;129:1045–1047. - PubMed

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