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Case Reports
. 2023 Apr 20;10(4):e01037.
doi: 10.14309/crj.0000000000001037. eCollection 2023 Apr.

Synchronous Pancreatic Masses

Arjun Chatterjee  1 , Neha Sharma  2 , Amandeep Singh  3 , Matthew Franklin  4 , Rajat Garg  3 , Prabhleen Chahal  3
Affiliations
Case Reports

Synchronous Pancreatic Masses

Arjun Chatterjee et al. ACG Case Rep J. .

Abstract

Any mass lesion in the pancreas usually raises the possibility of undiagnosed pancreatic cancer. With the advancement of imaging modalities, we are seeing an increasing number of incidental findings, some of which may be clinically significant. When dealing with incidental pancreatic findings, it is critical to keep a broad differential in mind in addition to ruling out pancreatic malignancy. We present 3 rare cases of patients with 2 or more synchronous solid masses in the pancreas caused by pancreatic cancer, type 1 autoimmune pancreatitis, and sarcoidosis.

Keywords: autoimmune pancreatitis; pancreatic ductal adenocarcinoma; pancreatic sarcoidosis; synchronous pancreatic masses.

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Figures

Figure 1.
Figure 1.
Abdominal contrast-enhanced computed tomography demonstrating 2 solid masses in the body (blue arrow, panel A) and tail of the pancreas (yellow arrow, panel B).
Figure 2.
Figure 2.
Endoscopic ultrasound demonstrating the 2 irregular mass-like processes, hypoechoic in the pancreatic body (panel A) and heterogenous in the pancreatic tail (panel B).
Figure 3.
Figure 3.
Abdominal contrast-enhanced computed tomography demonstrating infiltrative changes throughout the pancreas and the classic “sausage-shaped” appearance in autoimmune pancreatitis type 1.
Figure 4.
Figure 4.
Endoscopic ultrasound with fine needle biopsy of one of the hypoechoic heterogenous mass-like lesions.
Figure 5.
Figure 5.
Endoscopic ultrasound demonstrating several heterogenous, infiltrative masses with ill-defined borders.
Figure 6.
Figure 6.
Hematoxylin and eosin, 200× magnification. High-power view of a sarcoidal granuloma.
See this image and copyright information in PMC

References

    1. Bittorf B, Kessler H, Merkel S, et al. . Multiple primary malignancies: An epidemiological and pedigree analysis of 57 patients with at least three tumours. Eur J Surg Oncol. 2001;27(3):302–13. - PubMed
    1. Mehdi I, Shah AH, Moona MS, et al. . Synchronous and metachronous malignant tumours expect the unexpected. J Pak Med Assoc. 2010;60(11):905–9. - PubMed
    1. Sastry A, Wayne M, Steele J, Iskandar M, Yuan S, Cooperman AM. Three synchronous, sporadic and separate periampullary and pancreatic tumors: More than a coincidence? World J Surg Oncol. 2014;12(1):382. - PMC - PubMed
    1. Shiokawa M, Kodama Y, Hiramatsu Y, et al. . Autoimmune pancreatitis exhibiting multiple mass lesions. Case Rep Gastroenterol. 2011;5(3):528–33. - PMC - PubMed
    1. Fujimori N, Nakamura T, Oono T, et al. . Adenocarcinoma involving the whole pancreas with multiple pancreatic masses. Intern Med. 2010;49(15):1527–32. - PubMed

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