Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2023 Mar;35(3):233-243.
doi: 10.1016/j.sdentj.2023.01.010. Epub 2023 Feb 6.

Chemomechanical caries removal methods: A literature review

Manal S Maashi  1   2 , Heba M Elkhodary  1   3 , Najlaa M Alamoudi  1 , Nada O Bamashmous  1
Affiliations
Review

Chemomechanical caries removal methods: A literature review

Manal S Maashi et al. Saudi Dent J. 2023 Mar.

Abstract

Aim: To provide dental practitioners and researchers with a comprehensive review of the historical development, chemical composition, mechanisms of action, advantages, and drawbacks of different chemomechanical caries removal (CMCR) agents.

Methods: An electronic search was performed for all articles published on CMCR agents in various databases, including the Web of Science, PubMed, Cochrane, Scopus, and Google Scholar bibliographic databases, from January 1, 1975, to July 31, 2022.

Results: Records were identified using the following search terms: Brix3000, Carie-Care, Caridex, Carisolv, chemomechanical caries removal, conventional surgical method, and Papacárie. A total of 171 articles were screened based on the titles and abstracts, of which 126 were deemed eligible for inclusion after duplicates were removed. Following a manual search of the reference list, eight articles were added. Articles were then excluded for other reasons, such as being written before 1975, being written in a language other than English, and the non-availability of the full text. Overall, 120 articles were included in the analysis (literature reviews [n = 27], systematic reviews [n = 8], research articles [n = 82], case reports [n = 3]).

Conclusion: CMCR is a potential method of caries control in the future as an alternative to the conventional surgical approach in standard dentistry applications. It is more widely accepted, less painful, and has comparable efficacy to the conventional surgical method.

Clinical significance: A continuous trend among manufacturers has been observed since 1975 to reduce the drawbacks of CMCR agents. Moreover, evidence-based minimally invasive techniques, including CMCR agents that require minimal or no aerosol-generating procedures, are preferred while measures to control the spread of coronavirus disease are in force.

Keywords: Brix3000; Caridex; Carie-Care; Carisolv; Chemomechanical caries removal; Papacárie.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Flow chart of the literature research process.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Abdelaziz E., Badran A., Allam G. Chemomechanical caries removal agents and their applications in pediatric dentistry. Adv. Dent. J. 2022;4(1):11–18.
    1. Albrektsson T., Bratthall D., Glantz P.O.J. first ed. Quintessence Publishing Company; London: 2001. Tissue preservation in caries treatment.
    1. Al-Halabi M., Salami A., Alnuaimi E., Kowash M., Hussein I. Assessment of paediatric dental guidelines and caries management alternatives in the post COVID-19 period. A critical review and clinical recommendations. Eur. Arch. Paediatr. Dent. 2020;21(5):543–556. - PMC - PubMed
    1. Alkhouli M.M., Al Nesser S.F., Bshara N.G., AlMidani A.N., Comisi J.C. Comparing the efficacies of two chemo-mechanical caries removal agents (2.25% sodium hypochlorite gel and brix 3000), in caries removal and patient cooperation: A randomized controlled clinical trial. J. Dent. 2020;93(1):103280–103285. - PubMed
    1. Almaz M.E., Sönmez I.Ş., Oba A.A. Comparison of chemomechanical caries removal using Papacárie versus conventional method in children. Eur. J. Gen. Dent. 2016;5(1):1–5.

LinkOut - more resources